Gefitinib-Induced Cutaneous Toxicities in Brown Norway Rats Are Associated with Macrophage Infiltration.
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation"
DOI: 10.1007/s10753-020-01281-2
Abstract: Gefitinib (Iressa), is a selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), used in the targeted treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC). Skin toxicity is the major adverse… read more here.
Keywords: gefitinib induced; gefitinib; macrophage infiltration; cutaneous toxicities ... See more keywords
Oxidative stress and macrophage infiltration in IgA nephropathy
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DOI: 10.1007/s40620-021-01196-7
Abstract: The aim of this study was to evaluate the interactions among serum levels of galactose-deficient IgA1 (Gd-IgA1), oxidative stress and macrophage infiltration and their clinical correlates in patients with IgA Nephropathy (IgAN). A total of… read more here.
Keywords: stress macrophage; iga nephropathy; iga1; macrophage infiltration ... See more keywords
Schwann cell-derived CXCL1 contributes to human immunodeficiency virus type 1 gp120-induced neuropathic pain by modulating macrophage infiltration in mice
Sign Up to like & getrecommendations! Published in 2020 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2020.03.027
Abstract: The neuroinflammatory responses to human immunodeficiency virus type 1 (HIV-1) coat proteins, such as glycoprotein 120 (gp120), are considered to be responsible for the HIV-associated distal sensory neuropathy. Accumulating evidences suggest that T-cell line tropic… read more here.
Keywords: schwann; infiltration; gp120; macrophage infiltration ... See more keywords
Loganin alleviates macrophage infiltration and activation by inhibiting the MCP-1/CCR2 axis in diabetic nephropathy.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118808
Abstract: BACKGROUND/AIMS The theory of inflammation is one of the important theories in the pathogenesis of diabetic nephropathy (DN). We herein aimed to explore whether loganin affected macrophage infiltration and activation upon diabetic nephropathy (DN) by… read more here.
Keywords: loganin; ccr2; infiltration activation; macrophage infiltration ... See more keywords
Trelagliptin Mitigates Macrophage Infiltration by Preventing the Breakdown of the Blood-Brain Barrier in the Brain of Middle Cerebral Artery Occlusion Mice.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.0c00323
Abstract: Stroke is a significant cardiovascular disease that influences the health of human beings all over the world, especially the elderly population. It is reported that the blood-brain barrier (BBB) can be easily destroyed by stroke,… read more here.
Keywords: blood brain; brain; brain barrier; macrophage infiltration ... See more keywords
ATRX-dependent SVCT2 mediates macrophage infiltration in the glioblastoma xenograft model.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurophysiology"
DOI: 10.1152/jn.00486.2021
Abstract: Alpha thalassemia/mental retardation syndrome X-linked (ATRX) mutation impairs DNA damage repair in glioblastoma (GBM), making these cells more susceptible to treatment, which may contribute to the survival advantage in GBM patients containing ATRX mutations. To… read more here.
Keywords: dependent svct2; model; svct2; atrx dependent ... See more keywords
Anthocyanins Function as Anti-Inflammatory Agents in a Drosophila Model for Adipose Tissue Macrophage Infiltration
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/6413172
Abstract: Epidemiological and preclinical studies have demonstrated that bioactive foods like flavonoids, polyphenolic compounds derived from fruits and vegetables, exert a protective action against obesity, cardiovascular disorders, and Adipocyte Tissue Macrophage infiltration (ATM). All these pathologies… read more here.
Keywords: drosophila model; tissue macrophage; macrophage infiltration; tissue ... See more keywords
Protective Prognostic Biomarkers Negatively Correlated with Macrophage M2 Infiltration in Low-Grade Glioma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/3623591
Abstract: Tumor-associated Macrophages (TAMs) play a vital role in the progression of glioma. Macrophage M2 has been confirmed to promote immunosuppression and proliferation of low-grade glioma (LGG). Here, we searched for genes negatively correlated with Macrophages… read more here.
Keywords: infiltration; grade glioma; negatively correlated; glioma ... See more keywords
Macrophage Infiltration Reduces Neurodegeneration and Improves Stroke Recovery after Delayed Recanalization in Rats
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/6422202
Abstract: Background Recent cerebrovascular recanalization therapy clinical trials have validated delayed recanalization in patients outside of the conventional window. However, a paucity of information on the pathophysiology of delayed recanalization and favorable outcomes remains. Since macrophages… read more here.
Keywords: delayed recanalization; recanalization; neurodegeneration; macrophage infiltration ... See more keywords
Cop1 Controls Macrophage Infiltration and Antitumor Immunity in TNBC.
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DOI: 10.1158/2159-8290.cd-rw2021-144
Abstract: Knockout of Cop1 inhibits M2 macrophage infiltration and enhances immunotherapy response in TNBC. read more here.
Keywords: cop1; controls macrophage; cop1 controls; macrophage infiltration ... See more keywords
Abstract A87: Acetaminophen pretreatment stimulated interferon γ-induced PD-L1 protein expression in vitro and CD68 positive macrophage infiltration in tumor xenograft
Sign Up to like & getrecommendations! Published in 2020 at "Cancer immunology research"
DOI: 10.1158/2326-6074.tumimm18-a87
Abstract: Immunotherapy targeting the programmed cell death ligand 1/programmed cell death protein 1 (PD-L1/PD-1) pathway using antibodies is clinically effective in treating a spectrum of cancers. Acetaminophen (AAP) has shown antitumor and/or chemo-enhancing effects in human… read more here.
Keywords: expression; immunology; tumor; macrophage infiltration ... See more keywords