Use of Ultra‐Low Attachment Flasks Aids Manufacturing of the Macrophage‐Like Cell Therapy Product DUOC‐01 but Changes Product Phenotype
Sign Up to like & getrecommendations! Published in 2019 at "STEM CELLS Translational Medicine"
DOI: 10.1002/sctm.12569
Abstract: 20 Introduction DUOC-01 cells are a macrophage-like cell therapy product derived from umbilical cord blood that is currently being evaluated in a phase I clinical trial for patients with congenital lysosomal storage diseases (ClinicalTrials.gov Identifier:… read more here.
Keywords: like cell; duoc; macrophage like; cell therapy ... See more keywords
In Vitro Infections of Macrophage-Like Cell Lines with Leishmania infantum for Drug Screening.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9210-2_14
Abstract: The study of in vitro infections is essential to evaluate distinct aspects of Leishmania biology and also invaluable for more meaningful in vitro screening of promising chemical entities. Macrophage-like cells lines from different origins are… read more here.
Keywords: macrophage like; cell lines; vitro infections; biology ... See more keywords
Development of an In Vitro Model of Inflammatory Cytokine Influences on Intervertebral Disk Cells in 3D Cell Culture Using Activated Macrophage-Like THP-1 Cells
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4304-6
Abstract: We developed a new model for evaluation of the influence of proinflammatory cytokines on intervertebral disc cells in a 3D culture based on co-culturing of these cells with activated macrophage-like THP-1 cells. The levels of… read more here.
Keywords: macrophage like; model; activated macrophage; culture ... See more keywords
Culture media-based selection of endothelial cells, pericytes, and perivascular-resident macrophage-like melanocytes from the young mouse vestibular system
Sign Up to like & getrecommendations! Published in 2017 at "Hearing Research"
DOI: 10.1016/j.heares.2016.12.012
Abstract: &NA; The vestibular blood‐labyrinth barrier (BLB) is comprised of perivascular‐resident macrophage‐like melanocytes (PVM/Ms) and pericytes (PCs), in addition to endothelial cells (ECs) and basement membrane (BM), and bears strong resemblance to the cochlear BLB in… read more here.
Keywords: macrophage like; like melanocytes; culture; cell ... See more keywords
C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse.
Sign Up to like & getrecommendations! Published in 2022 at "Blood"
DOI: 10.1182/blood.2022017046
Abstract: Extramedullary infiltration (EMI) is a concomitant manifestation that may indicate poor outcome of acute myeloid leukemia (AML). The underlying mechanism remains poorly understood and therapeutic options are limited. Here, we employed single-cell RNA sequencing on… read more here.
Keywords: infiltration; c1q; like leukemia; macrophage like ... See more keywords
Transcriptome profiling of antiviral immune and dietary fatty acid dependent responses of Atlantic salmon macrophage-like cells
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-4099-2
Abstract: BackgroundDue to the limited availability and high cost of fish oil in the face of increasing aquaculture production, there is a need to reduce usage of fish oil in aquafeeds without compromising farm fish health.… read more here.
Keywords: macrophage like; like cells; pic; fish oil ... See more keywords
Impact of the flame retardant 2,2’4,4’-tetrabromodiphenyl ether (PBDE-47) in THP-1 macrophage-like cell function via small extracellular vesicles
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1069207
Abstract: 2,2’4,4’-tetrabromodiphenyl ether (PBDE-47) is one of the most widespread environmental brominated flame-retardant congeners which has also been detected in animal and human tissues. Several studies have reported the effects of PBDEs on different health issues,… read more here.
Keywords: thp macrophage; tetrabromodiphenyl ether; ether pbde; like cells ... See more keywords
Characterization of Macrophage-Like Cells in Retinal Vein Occlusion Using En Face Optical Coherence Tomography
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.855466
Abstract: Purpose To investigate the clinical features of a macrophage-like cell (MLC) obtained by en face optical coherence tomography (OCT) in retinal vein occlusion (RVO). Methods The study involved 36 patients with treatment-naïve unilateral acute RVO,… read more here.
Keywords: density; region; face optical; rvo ... See more keywords
Opinion: Endothelial Cells - Macrophage-Like Gatekeepers?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.902945
Abstract: Endothelial cells are known to form a single-cell layer of endothelium that plays an important role in cardiovascular homeostasis by regulating blood fluidity, fibrinolysis, vascular tone and permeability, angiogenesis, monocyte adhesion, and platelet aggregation (1).… read more here.
Keywords: ecs macrophages; endothelial cells; opinion; like gatekeepers ... See more keywords
Ergosta-7,9(11),22-trien-3β-ol Attenuates Inflammatory Responses via Inhibiting MAPK/AP-1 Induced IL-6/JAK/STAT Pathways and Activating Nrf2/HO-1 Signaling in LPS-Stimulated Macrophage-like Cells
Sign Up to like & getrecommendations! Published in 2021 at "Antioxidants"
DOI: 10.3390/antiox10091430
Abstract: Chronic inflammation induces autoimmune disorders and chronic diseases. Several natural products activate nuclear factor erythroid 2-related factor 2 (Nrf2) signaling, attenuating inflammatory responses. Ergosta-7,9(11),22-trien-3β-ol (EK100) isolated from Cordyceps militaris showed anti-inflammatory and antioxidative activity, but… read more here.
Keywords: inflammatory responses; macrophage like; lps stimulated; jak stat ... See more keywords
Macrophage-like THP-1 Cells Derived from High-Density Cell Culture Are Resistant to TRAIL-Induced Cell Death via Down-Regulation of Death-Receptors DR4 and DR5
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12020150
Abstract: Simple Summary The mechanisms of leukemic cell resistance to antitumor immunity remains a topical issue. In this work, we found an increase in TRAIL-resistance of human acute myeloid leukemia cells THP-1 in high-density populations in… read more here.
Keywords: high density; resistance; trail; death ... See more keywords