Aquaporin-1 attenuates macrophage-mediated inflammatory responses by inhibiting p38 mitogen-activated protein kinase activation in lipopolysaccharide-induced acute kidney injury
Sign Up to like & getrecommendations! Published in 2019 at "Inflammation Research"
DOI: 10.1007/s00011-019-01285-1
Abstract: This study was designed to investigate the role of AQP1 in the development of LPS-induced AKI and its potential regulatory mechanisms in the inflammatory responses of macrophages. Male Wistar rats were injected intraperitoneally with LPS,… read more here.
Keywords: p38 mapk; inflammatory responses; macrophage mediated; p38 ... See more keywords
Crushed Gold Shell Nanoparticles Labeled with Radioactive Iodine as a Theranostic Nanoplatform for Macrophage-Mediated Photothermal Therapy
Sign Up to like & getrecommendations! Published in 2019 at "Nano-Micro Letters"
DOI: 10.1007/s40820-019-0266-0
Abstract: HighlightsCrushed gold shell radionuclide nanoballs (124I-Au@AuCBs) were fabricated as unique photothermal therapeutics and nuclear medicine imaging nanoplatforms.Macrophage-mediated delivery of 124I-Au@AuCBs and their potential photothermal therapy applications were demonstrated in mice with colon cancer.AbstractPlasmonic nanostructure-mediated photothermal… read more here.
Keywords: 124i aucbs; macrophage mediated; gold; macrophage ... See more keywords
Unveiling the fate of adhering bacteria to antimicrobial surfaces: expression of resistance-associated genes and macrophage-mediated phagocytosis.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.07.052
Abstract: Since most antibacterial coatings reported to fight biomaterial-associated infections (BAI) fail in completely preventing bacterial colonization, it is crucial to know the impact of that small fraction of adhered bacteria in BAI recrudescence. This study… read more here.
Keywords: mediated phagocytosis; macrophage mediated; fate; resistance ... See more keywords
Mifepristone regulates macrophage-mediated natural killer cells function in decidua.
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive biology"
DOI: 10.1016/j.repbio.2021.100541
Abstract: Mifepristone has been used for first-trimester abortion and contraception. Nevertheless, its functional mechanism still needs to be elucidated. Decidua tissues were collected from 40 pregnant women who received (20 patients) or did not receive (20… read more here.
Keywords: mifepristone; mifepristone regulates; macrophage mediated; tgf ... See more keywords
Macrophage-Mediated Exocytosis of Elongated Nanoparticles Improves Hepatic Excretion and Cancer Phototherapy.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b10302
Abstract: The introduction of nanoparticle-mediated delivery and therapy has revolutionized cancer treatment approaches. However, there has been limited success in clinical trials because current approaches have not simultaneously satisfied therapeutic efficacy and biosafety criteria to an… read more here.
Keywords: excretion; mediated exocytosis; macrophage mediated; cancer ... See more keywords
MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses
Sign Up to like & getrecommendations! Published in 2022 at "Oncogene"
DOI: 10.1038/s41388-022-02236-7
Abstract: Macrophage-mediated tumor cell phagocytosis and subsequent neoantigen presentation are critical for generating anti-tumor immunity. This study aimed to uncover the potential clinical value and molecular mechanisms of miRNA-22 (miR-22) in tumor cell phagocytosis via macrophages… read more here.
Keywords: tumor; cell phagocytosis; cell; macrophage mediated ... See more keywords
AB0248 Evaluation of subcutaneously (SC) injected tc 99m tilmanocept localization in active rheumatoid arthritis (RA) subjects by planar and spect/ct
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.7533
Abstract: Background In rheumatoid arthritis (RA), infiltrating macrophages play a critical role in the immunopathogenesis of the disease by generating pro-inflammatory cytokines and chemokines and by contributing directly to joint damage. Current imaging modalities do not… read more here.
Keywords: none declared; inflammation; macrophage mediated; cohort ... See more keywords
Abstract 2957: CD127 is expressed by acute lymphoblastic leukemias and is efficiently targeted by the IL7R-antagonist OSE-127 through macrophage-mediated antibody dependent phagocytosis
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2957
Abstract: Acute lymphoblastic leukemia (ALL) arises from the uncontrolled proliferation of precursor B or T cells (B- or T-ALL). Novel immunotherapies are urgently needed to reduce polychemotherapy-related toxicities and to target relapsed/refractory disease. The Interleukin 7… read more here.
Keywords: macrophage mediated; cd127; antagonist; ose 127 ... See more keywords
Recent Advances in Macrophage-Mediated Drug Delivery Systems
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s298159
Abstract: Abstract Macrophages have been extensively used in the development of drug delivery systems, as they can prolong the circulation and release of drugs, extend their half-life, increase their stability and targeting ability, and reduce immunogenicity.… read more here.
Keywords: macrophage mediated; drug; mediated drug; drug delivery ... See more keywords
Macrophage Mediated Immunomodulation During Cryptococcus Pulmonary Infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.859049
Abstract: Macrophages are key cellular components of innate immunity, acting as the first line of defense against pathogens to modulate homeostatic and inflammatory responses. They help clear pathogens and shape the T-cell response through the production… read more here.
Keywords: macrophage mediated; infection; cryptococcus; mediated immunomodulation ... See more keywords
Macrophage-Mediated Tissue Vascularization: Similarities and Differences Between Cornea and Skin
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.667830
Abstract: Macrophages are critical mediators of tissue vascularization both in health and disease. In multiple tissues, macrophages have been identified as important regulators of both blood and lymphatic vessel growth, specifically following tissue injury and in… read more here.
Keywords: macrophage mediated; vascularization; tissue vascularization; cornea skin ... See more keywords