Alternations in inflammatory macrophage niche drive phenotypic and functional plasticity of Kupffer cells
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DOI: 10.1038/s41467-024-53659-7
Abstract: Inflammatory signals lead to recruitment of circulating monocytes and induce their differentiation into pro-inflammatory macrophages. Therefore, whether blocking inflammatory monocytes can mitigate disease progression is being actively evaluated. Here, we employ multiple lineage-tracing models and… read more here.
Keywords: kupffer cells; macrophage niche; macrophage; niche ... See more keywords
An Eye on Kupffer Cells: Development, Phenotype and the Macrophage Niche
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179868
Abstract: Macrophages are key participants in the maintenance of tissue homeostasis under normal and pathological conditions, and implement a rich diversity of functions. The largest population of resident tissue macrophages is found in the liver. Hepatic… read more here.
Keywords: macrophage niche; kupffer cells; macrophage; eye kupffer ... See more keywords