Macrophage-Mediated Tumor Cell Phagocytosis: Opportunity for Nanomedicine Intervention.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced functional materials"
DOI: 10.1002/adfm.202006220
Abstract: Macrophages are one of the most abundant non-malignant cells in the tumor microenvironment, playing critical roles in mediating tumor immunity. As important innate immune cells, macrophages possess the potential to engulf tumor cells and present… read more here.
Keywords: intervention; macrophage phagocytosis; phagocytosis; tumor cells ... See more keywords
Zwitterionic Brush‐Grafted Interfacial Bio‐Lubricant Evades Complement C3‐Mediated Macrophage Phagocytosis for Osteoarthritis Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Materials"
DOI: 10.1002/adma.202501137
Abstract: Administering a bio‐lubricant is a promising therapeutic approach for the treatment of osteoarthritis (OA), in particular, if it can both manage symptoms and halt disease progression. However, the clearance of these bio‐lubricants mediated by synovial… read more here.
Keywords: bio lubricant; macrophage phagocytosis; bio; macrophage ... See more keywords
Macrophage phagocytosis cracking the defect code in COPD
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical Journal"
DOI: 10.1016/j.bj.2017.09.004
Abstract: In the normal non-diseased lung, various macrophage populations maintain homeostasis and sterility by ingesting and clearing inhaled particulates, pathogens and apoptotic cells from the local environment. This process of phagocytosis leads to the degradation of… read more here.
Keywords: macrophage phagocytosis; phagocytosis; defect code; cracking defect ... See more keywords
Minthostachys verticillata essential oil activates macrophage phagocytosis and modulates the innate immune response in a murine model of Enterococcus faecium mastitis.
Sign Up to like & getrecommendations! Published in 2019 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2019.07.015
Abstract: Minthostachys verticillata essential oil (EO) is a natural product that reports immunomodulatory effects on human T cells as well as anti-inflammatory activity. Bovine mastitis is a worldwide disease, mainly caused by bacteria, affecting milk quality… read more here.
Keywords: macrophage phagocytosis; minthostachys verticillata; faecium; mastitis ... See more keywords
Abnormal HCK/glutamine/autophagy axis promotes endometriosis development by impairing macrophage phagocytosis
Sign Up to like & getrecommendations! Published in 2024 at "Cell Proliferation"
DOI: 10.1111/cpr.13702
Abstract: The presence of extensive infiltrated macrophages with impaired phagocytosis is widely recognised as a significant regulator for the development of endometriosis (EMs). Nevertheless, the metabolic characteristics and the fundamental mechanism of impaired macrophage phagocytosis are… read more here.
Keywords: macrophage phagocytosis; phagocytosis; macrophage; autophagy ... See more keywords
DLBCL-Derived HMGB2 Inhibits Macrophage Phagocytosis By up-Regulating TRIM65 to Promote NLRP3 Ubiquitination
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-206478
Abstract: Background： Diffuse large B-cell lymphoma (DLBCL), the predominant non-Hodgkin lymphoma type, exhibits significant clinical and biological heterogeneity. Despite favorable outcomes with R-CHOP therapy in most cases, approximately 30-40% of patients experience disease progression or relapse.… read more here.
Keywords: dlbcl; macrophage phagocytosis; hmgb2; cell ... See more keywords
Serum from half of immune thrombocytopenia patients trigger macrophage phagocytosis of platelets.
Sign Up to like & getrecommendations! Published in 2023 at "Blood advances"
DOI: 10.1182/bloodadvances.2022009423
Abstract: The accelerated clearance of platelets is a central feature of immune thrombocytopenia (ITP) pathophysiology. The Harrington-Hollingsworth experiment provided evidence that accelerated platelet clearance may be due to factors present in ITP patient circulation. Harrington et… read more here.
Keywords: clearance; immune thrombocytopenia; itp; platelet ... See more keywords
Elevated heme impairs macrophage phagocytosis in endometriosis.
Sign Up to like & getrecommendations! Published in 2019 at "Reproduction"
DOI: 10.1530/rep-19-0028
Abstract: Endometriosis (EMS) is a chronic inflammatory disease characterized by the presence of extrauterine endometrial tissues. It has been previously reported that the refluxed blood containing viable endometrial tissues and the defective elimination of peritoneal macrophages… read more here.
Keywords: macrophage; endometriosis; macrophage phagocytosis; elevated heme ... See more keywords
Irisin alleviated sepsis via enhancing macrophage phagocytosis and reducing inflammation levels
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1618699
Abstract: Background The treatment of sepsis relies on antibiotics following infection; however, the emergence of resistant bacteria necessitates the development of new therapeutic agents. Irisin has been shown to alleviate symptoms in septic mice, although its… read more here.
Keywords: macrophage phagocytosis; sepsis; irisin; inflammation ... See more keywords