Anti-Fibrotic Drug Nintedanib Inhibits CSF1R to Promote IL-4-associated Tissue Repair Macrophages.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2022-0021oc
Abstract: Pro-fibrotic and pro-homeostatic macrophage phenotypes remain ill-defined, both in vivo and in vitro impeding successful development of drugs that reprogram macrophages as an attractive therapeutic approach to manage fibrotic disease. The goal to of this… read more here.
Keywords: macrophage phenotypes; tissue repair; nintedanib; anti fibrotic ... See more keywords
Transcriptomic Establishment of Pig Macrophage Polarization Signatures
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DOI: 10.3390/cimb45030151
Abstract: Macrophages are the foremost controllers of innate and acquired immunity, playing important roles in tissue homeostasis, vasculogenesis, and congenital metabolism. In vitro macrophages are crucial models for understanding the regulatory mechanism of immune responses and… read more here.
Keywords: macrophage polarization; macrophage phenotypes; pig macrophage; establishment pig ... See more keywords
Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18071545
Abstract: Macrophages and inflammation play a beneficial role during wound repair with macrophages regulating a wide range of processes, such as removal of dead cells, debris and pathogens, through to extracellular matrix deposition re-vascularisation and wound… read more here.
Keywords: scar; wound healing; macrophage phenotypes; scar formation ... See more keywords
Label-Free Characterization of Macrophage Polarization Using Raman Spectroscopy
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010824
Abstract: Macrophages are important cells of the innate immune system that play many different roles in host defense, a fact that is reflected by their polarization into many distinct subtypes. Depending on their function and phenotype,… read more here.
Keywords: label free; macrophage phenotypes; spectroscopy; characterization macrophage ... See more keywords
Biologic Mechanisms of Macrophage Phenotypes Responding to Infection and the Novel Therapies to Moderate Inflammation
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24098358
Abstract: Pro-inflammatory and anti-inflammatory types are the main phenotypes of the macrophage, which are commonly notified as M1 and M2, respectively. The alteration of macrophage phenotypes and the progression of inflammation are intimately associated; both phenotypes… read more here.
Keywords: inflammation; macrophage phenotypes; phenotypes responding; mechanisms macrophage ... See more keywords
Blackcurrant (Ribes nigrum) Extract Exerts an Anti-Inflammatory Action by Modulating Macrophage Phenotypes
Sign Up to like & getrecommendations! Published in 2019 at "Nutrients"
DOI: 10.3390/nu11050975
Abstract: Macrophages are polarized into different phenotypes depending on tissue microenvironment where they reside. In obesity-associated inflammation, M1-type macrophages are predominant in the inflamed tissue, exerting pro-inflammatory responses. Our previous studies demonstrate that blackcurrant consumption attenuates… read more here.
Keywords: anti inflammatory; macrophage phenotypes; inflammatory action; pro inflammatory ... See more keywords
Deciphering Macrophage Phenotypes upon Lipid Uptake and Atherosclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Immune Network"
DOI: 10.4110/in.2020.20.e22
Abstract: In the progression of atherosclerosis, macrophages are the key immune cells for foam cell formation. During hyperlipidemic condition, phagocytic cells such as monocytes and macrophages uptake oxidized low-density lipoproteins (oxLDLs) accumulated in subintimal space, and… read more here.
Keywords: deciphering macrophage; phenotypes upon; macrophage phenotypes; macrophage ... See more keywords