Transcriptional control of macrophage polarisation in type 2 diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-019-00748-1
Abstract: Type-2 diabetes (T2D) is considered today as an inflammatory disease. Inflammatory processes in T2D are orchestrated by macrophage activation in different organs. Macrophages undergo classical M1 pro-inflammatory or alternative M2 anti-inflammatory activation in response to… read more here.
Keywords: transcriptional control; macrophage polarisation; type diabetes; macrophage ... See more keywords
Role of macrophage polarisation in skin wound healing.
Sign Up to like & getrecommendations! Published in 2023 at "International wound journal"
DOI: 10.1111/iwj.14119
Abstract: Skin wound healing is a complex pathophysiological change that is driven by macrophages and their secreted related factors. Depending on the stimuli, macrophages can be polarised into two subtypes of macrophages with completely different phenotypes… read more here.
Keywords: role; skin wound; macrophage polarisation; wound healing ... See more keywords
THU0056 14–3–3 is a molecular switch regulating macrophage polarisation in inflammatory arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.4729
Abstract: Background Functional heterogeneity is a hallmark of macrophages, which can classified into 2 major phenotypes with opposite role in inflammation termed M1 (inflammatory or classically activated) macrophages and M2 (alternatively activated) macrophages. In addition, M1-M2… read more here.
Keywords: polarisation; macrophage polarisation; inflammatory arthritis; pgrn ... See more keywords
In vivo single‐cell transcriptomics reveal Klebsiella pneumoniae skews lung macrophages to promote infection
Sign Up to like & getrecommendations! Published in 2022 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.202216888
Abstract: The strategies deployed by antibiotic‐resistant bacteria to counteract host defences are poorly understood. Here, we elucidate a novel host–pathogen interaction resulting in skewing lung macrophage polarisation by the human pathogen Klebsiella pneumoniae. We identify interstitial… read more here.
Keywords: klebsiella pneumoniae; klebsiella; lung macrophages; lung ... See more keywords