Increased Expression of Glutaminase in Osteoblasts Promotes Macrophage Recruitment in Periapical Lesions
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Endodontics"
DOI: 10.1016/j.joen.2016.11.005
Abstract: Introduction Recently, we have shown that tissue hypoxia stimulates the progression of periapical lesions by up‐regulating glycolysis‐dependent apoptosis of osteoblasts. Other facets of hypoxia‐induced metabolic reprogramming in disease pathogenesis require further investigation. In this study,… read more here.
Keywords: periapical lesions; glutaminase; macrophage recruitment; gls1 ... See more keywords
PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42846
Abstract: Macrophages have been demonstrated to play a proangiogenic role in retinal pathological vascular growth. Pigment epithelium-derived factor (PEDF) works as a powerful endogenous angiogenesis inhibitor, but its role in macrophage recruitment and polarization is largely… read more here.
Keywords: pedf; macrophage recruitment; polarization; recruitment polarization ... See more keywords
Angiotensin II–C–C chemokine receptor2/5 axis‐dependent monocyte/macrophage recruitment contributes to progression of experimental autoimmune myocarditis
Sign Up to like & getrecommendations! Published in 2017 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.12548
Abstract: Angiotensin II (ANG II) plays critical roles in modulation of circulatory homeostasis and activation of innate and adaptive immunity and has also been implicated in several mouse models of autoimmune disease. However, how ANG II… read more here.
Keywords: autoimmune myocarditis; macrophage recruitment; monocyte macrophage; macrophage ... See more keywords
Cross‐talk between ovarian cancer cells and macrophages through periostin promotes macrophage recruitment
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Science"
DOI: 10.1111/cas.13567
Abstract: Tumor‐associated macrophages (TAMs) contribute to tumor progression, but it is not clear how they are recruited to tumor sites. Here we showed that periostin (POSTN) was present at high levels in ovarian cancer ascetic fluids… read more here.
Keywords: cross talk; macrophage recruitment; ovarian cancer; cancer cells ... See more keywords
HMGA1 Promotes Macrophage Recruitment via Activation of NF-κB-CCL2 Signaling in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/4727198
Abstract: Background Tumor-associated macrophages (TAMs) are known to generate an immune-suppressive tumor microenvironment (TME) and promote tumor progression. Hepatocellular carcinoma (HCC) is a devastating disease that evolves in the background of chronic inflammatory liver damage. In… read more here.
Keywords: hepatocellular carcinoma; macrophage recruitment; hcc; ccl2 ... See more keywords
Abstract LB009: Notch4 inhibition by a novel neutralizing antibody reduces tumor progression and increases macrophage recruitment within the tumor microenvironment
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb009
Abstract: The Notch signaling pathway, particularly endothelial Notch signaling, plays a key role in tumor formation and angiogenesis. Inhibiting Notch1 or its ligand, Delta-like ligand 4 (Dll4), can induce hypersprouting of the tumor vasculature and thus… read more here.
Keywords: macrophage recruitment; progression; notch4 inhibition; tumor ... See more keywords
SRC-3 deficiency prevents atherosclerosis development by decreasing endothelial ICAM-1 expression to attenuate macrophage recruitment
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.74864
Abstract: Steroid receptor coactivator 3 (SRC-3) is a member of the p160 SRC family. This factor can interact with multiple nuclear hormone receptors and transcription factors to regulate the expression of their target genes. Although many… read more here.
Keywords: macrophage recruitment; atherosclerosis development; expression; src ... See more keywords