Paeoniflorin inhibits the macrophage-related rosacea-like inflammatory reaction through the suppressor of cytokine signaling 3-apoptosis signal-regulating kinase 1-p38 pathway
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DOI: 10.1097/md.0000000000023986
Abstract: Supplemental Digital Content is available in the text Abstract Rosacea is a facial chronic inflammatory skin disease with immune and vascular system dysfunction. Paeoniflorin (PF) is a traditional Chinese medicine with anti-inflammatory properties. However, its… read more here.
Keywords: macrophage; medicine; related rosacea; macrophage related ... See more keywords
Development and validation of a novel M1 macrophage-related gene prognostic signature for lung cancer
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DOI: 10.21037/jtd-23-80
Abstract: Background Lung cancer (LC) is the most common cancer. Using data from The Cancer Genome Atlas (TCGA), we analyzed the functional roles of M1 macrophage status in LC patients. Methods Clinical and transcriptome data of… read more here.
Keywords: macrophage related; signature; macrophage; cancer ... See more keywords
Identification and exploration of novel M2 macrophage-related biomarkers in the development of acute myocardial infarction
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DOI: 10.3389/fcvm.2022.974353
Abstract: Background Acute myocardial infarction (AMI), one of the most severe and fatal cardiovascular diseases, is a major cause of morbidity and mortality worldwide. Macrophages play a critical role in ventricular remodeling after AMI. The regulatory… read more here.
Keywords: hub genes; macrophage related; hub; myocardial infarction ... See more keywords
Exploring the Immune Infiltration Landscape and M2 Macrophage-Related Biomarkers of Proliferative Diabetic Retinopathy
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DOI: 10.3389/fendo.2022.841813
Abstract: Backgrounds Diabetic retinopathy (DR), especially proliferative diabetic retinopathy (PDR), is the major cause of irreversible blindness in the working-age population. Increasing evidence indicates that immune cells and the inflammatory microenvironment play an important role during… read more here.
Keywords: macrophage related; pdr; expression; diabetic retinopathy ... See more keywords
Integrated bioinformatic analyses investigate macrophage-M1-related biomarkers and tuberculosis therapeutic drugs
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DOI: 10.3389/fgene.2023.1041892
Abstract: Tuberculosis (TB) is a common infectious disease linked to host genetics and the innate immune response. It is vital to investigate new molecular mechanisms and efficient biomarkers for Tuberculosis because the pathophysiology of the disease… read more here.
Keywords: macrophage related; biomarkers tuberculosis; tuberculosis therapeutic; macrophage ... See more keywords
Macrophage Related Chronic Inflammation in Non-Healing Wounds
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DOI: 10.3389/fimmu.2021.681710
Abstract: Persistent hyper-inflammation is a distinguishing pathophysiological characteristic of chronic wounds, and macrophage malfunction is considered as a major contributor thereof. In this review, we describe the origin and heterogeneity of macrophages during wound healing, and… read more here.
Keywords: macrophage related; inflammation; non healing; healing wounds ... See more keywords
Comprehensive Molecular Analyses of a Macrophage-Related Gene Signature With Regard to Prognosis, Immune Features, and Biomarkers for Immunotherapy in Hepatocellular Carcinoma Based on WGCNA and the LASSO Algorithm
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DOI: 10.3389/fimmu.2022.843408
Abstract: Macrophages have been reported to exert a crucial role in hepatocellular carcinoma (HCC). This study aimed to explore the macrophage-related genes and establish a macrophage-related signature (MRS) model to predict the overall survival (OS) of… read more here.
Keywords: gene; macrophage related; signature; mrs model ... See more keywords
Multi-omics analysis reveals a macrophage-related marker gene signature for prognostic prediction, immune landscape, genomic heterogeneity, and drug choices in prostate cancer
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DOI: 10.3389/fimmu.2023.1122670
Abstract: Introduction Macrophages are components of the innate immune system and can play an anti-tumor or pro-tumor role in the tumor microenvironment owing to their high heterogeneity and plasticity. Meanwhile, prostate cancer (PCa) is an immune-sensitive… read more here.
Keywords: heterogeneity; macrophage related; related marker; analysis ... See more keywords
Clinical M2 Macrophage-Related Genes Can Serve as a Reliable Predictor of Lung Adenocarcinoma
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DOI: 10.3389/fonc.2022.919899
Abstract: Background Numerous studies have found that infiltrating M2 macrophages play an important role in the tumor progression of lung adenocarcinoma (LUAD). However, the roles of M2 macrophage infiltration and M2 macrophage-related genes in immunotherapy and… read more here.
Keywords: macrophage related; lung adenocarcinoma; risk; related genes ... See more keywords