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   Articles with "macrophage reprogramming" as a keyword



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Macrophage Reprogramming with Anti‐miR223‐Loaded Artificial Protocells Enhances In Vivo Cancer Therapeutic Potential (Adv. Sci. 35/2022)

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recommendations! Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202202717

Abstract: Several immune cell‐expressed miRNAs (miRs) are associated with altered prognostic outcome in cancer patients, suggesting that they may be potential targets for development of cancer therapies. Here, translucent zebrafish (Danio rerio) is utilized to demonstrate… read more here.

Keywords: macrophage reprogramming; anti mir223; mir223; mir223 loaded ... See more keywords
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DDIT4 contributes to macrophage reprogramming

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recommendations! Published in 2021 at "Nature Reviews Endocrinology"

DOI: 10.1038/s41574-021-00614-x

Abstract: Obesity and nonalcoholic fatty liver disease (NAFLD) can reprogramme macrophages, leading to chronic inflammation and the development of nonalcoholic steatohepatitis (NASH). A study in Cell Reports investigated the role of an mRNAdestabilizing RNA modification, Nmethyladenosine… read more here.

Keywords: ddit4; contributes macrophage; ddit4 contributes; macrophage reprogramming ... See more keywords
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Macrophage reprogramming for therapy

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recommendations! Published in 2020 at "Immunology"

DOI: 10.1111/imm.13300

Abstract: Dysfunction of the immune system underlies a plethora of human diseases, requiring the development of immunomodulatory therapeutic intervention. To date, most strategies employed have been focusing on the modification of T lymphocytes, and although remarkable… read more here.

Keywords: reprogramming therapy; macrophage reprogramming; macrophage; immunology ... See more keywords
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GSK3β Inhibition Prevents Macrophage Reprogramming by High-Dose Methotrexate.

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recommendations! Published in 2022 at "Journal of innate immunity"

DOI: 10.1159/000526622

Abstract: Methotrexate (MTX) is an antifolate drug used as a chemotherapeutic agent for acute lymphoblastic leukemia, where MTX improves patients' prognosis. Macrophage reprogramming is being increasingly assessed as an antitumor therapeutic strategy. However, and although MTX… read more here.

Keywords: macrophage reprogramming; macrophage; gsk3 inhibition; methotrexate ... See more keywords