Independent Roles of Molecular Mobility and Zeta Potential on Supramolecular Surfaces in the Sequence of RAW264.7 Macrophage Responses.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200282
Abstract: Surface-properties of biomaterials affect the morphologies and inflammatory responses of macrophages. Recently, biomaterial-design utilizing these properties has been explored to build a scaffold for balancing the immune system in vivo. In the present study, polyrotaxane… read more here.
Keywords: mobility zeta; molecular mobility; mobility; macrophage responses ... See more keywords
Deubiquitinase USP12 promotes LPS induced macrophage responses through inhibition of IκBα.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.004
Abstract: Post translational modifications, ubiquitination and its reversal by deubiquitination play an important role in regulating innate immune system. USP12 is a poorly studied deubiquitinase reported to regulate T-cell receptor signalling however the functional role of… read more here.
Keywords: lps induced; usp12 promotes; macrophage; deubiquitinase usp12 ... See more keywords
Protein Adsorption on Surfaces Functionalized with COOH Groups Promotes Anti-inflammatory Macrophage Responses.
Sign Up to like & getrecommendations! Published in 2021 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c16509
Abstract: Implants can induce a foreign body reaction that leads to chronic inflammation and fibrosis in the surrounding tissue. Macrophages help detect the foreign material, play a role in the inflammatory response, and may promote fibrosis… read more here.
Keywords: anti inflammatory; cooh groups; adsorption; macrophage ... See more keywords
Functional Hallmarks of Healthy Macrophage Responses: Their Regulatory Basis and Disease Relevance.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of immunology"
DOI: 10.1146/annurev-immunol-101320-031555
Abstract: Macrophages are first responders for the immune system. In this role, they have both effector functions for neutralizing pathogens and sentinel functions for alerting other immune cells of diverse pathologic threats, thereby initiating and coordinating… read more here.
Keywords: regulatory basis; functional hallmarks; macrophage responses; healthy macrophage ... See more keywords
AMPK-driven Macrophage Responses are Autophagy-dependent in Experimental Bronchopulmonary Dysplasia.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2022-0282oc
Abstract: The pathogenesis of bronchopulmonary dysplasia (BPD) remains incompletely understood. Recent studies suggest insufficient adenosine monophosphate-activated protein kinase (AMPK) activation as a potential cause of impaired autophagy in rodent and non-human primate (NHP) models of BPD.… read more here.
Keywords: autophagy dependent; macrophage responses; ampk activation; bronchopulmonary dysplasia ... See more keywords
Avian Macrophage Responses to Virulent and Avirulent Clostridium perfringens
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11010100
Abstract: The present study evaluated the avian macrophage responses against Clostridium perfringens that varied in their ability to cause necrotic enteritis in chickens. Strains CP5 (avirulent-netB+), CP1 (virulent-netB+), and CP26 (highly virulent-netB+tpeL+) were used to evaluate… read more here.
Keywords: macrophage responses; clostridium perfringens; responses virulent; macrophage ... See more keywords