Single-Cell Insights Into Macrophage Subtypes in Pulmonary Infections.
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DOI: 10.1002/advs.202510758
Abstract: Macrophages are pivotal innate immune cells that play essential roles in pathogen recognition, inflammation modulation, and tissue repair during pulmonary infections. Macrophages have remarkable plasticity that is shaped by diverse external stimuli to adapt to… read more here.
Keywords: single cell; subtypes pulmonary; macrophage subtypes; macrophage ... See more keywords
Dissection of pro-tumoral macrophage subtypes and immunosuppressive cells participating in M2 polarization
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DOI: 10.1007/s00011-024-01907-3
Abstract: Alternatively activated macrophage (M2) polarization can result in one of four subtypes based on cytokines and signaling pathways associated with macrophage activation: M2a, M2b, M2c, and M2d macrophages. The majority of M2 subtypes are anti-inflammatory… read more here.
Keywords: macrophage polarization; pro tumoral; macrophage subtypes; macrophage ... See more keywords
A data-driven approach to establishing cell motility patterns as predictors of macrophage subtypes and their relation to cell morphology
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DOI: 10.1101/2022.11.29.518400
Abstract: The motility of macrophages in response to microenvironment stimuli is a hallmark of innate immunity, where macrophages play pro-inflammatory or pro-reparatory roles depending on their activation status during wound healing. Cell size and shape have… read more here.
Keywords: motility; macrophage subtypes; motility patterns; cell ... See more keywords
Deep learning classification for macrophage subtypes through cell migratory pattern analysis
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2024.1259037
Abstract: Macrophages can exhibit pro-inflammatory or pro-reparatory functions, contingent upon their specific activation state. This dynamic behavior empowers macrophages to engage in immune reactions and contribute to tissue homeostasis. Understanding the intricate interplay between macrophage motility… read more here.
Keywords: deep learning; classification; analysis; macrophage subtypes ... See more keywords