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   Articles with "macrophage survival" as a keyword



Deubiquitinase Mysm1 regulates macrophage survival and polarization

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recommendations! Published in 2018 at "Molecular Biology Reports"

DOI: 10.1007/s11033-018-4405-3

Abstract: Macrophages play pivotal roles in innate and adaptive immune response, tissue homeostasis and cancer development. Their development and heterogeneity are tightly controlled by epigenetic program and transcription factors. Deubiquitinase Mysm1 plays crucial roles in regulating… read more here.

Keywords: deubiquitinase mysm1; mysm1 macrophages; mysm1; polarization ... See more keywords

PLEKHO2 is essential for M-CSF-dependent macrophage survival.

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recommendations! Published in 2017 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2017.06.006

Abstract: Macrophage-colony stimulating factor (M-CSF) is crucial for macrophage survival; however, the mechanism associated with this signaling has not been fully elucidated. Here, we identified pleckstrin homology domain-containing family O member 2 (PLEKHO2), a protein with… read more here.

Keywords: csf; macrophage survival; macrophage; plekho2 essential ... See more keywords

Profile of tRNA-derived short non-coding RNAs during monocyte differentiation and their role in macrophage survival

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recommendations! Published in 2025 at "RNA Biology"

DOI: 10.1080/15476286.2025.2525886

Abstract: ABSTRACT Monocytes, a type of leukocytes, are key players in immune responses, transitioning to macrophages at infection sites. Differentiation, which is crucial for macrophage survival and resistance to apoptosis, is a tightly regulated process. Based… read more here.

Keywords: differentiation role; macrophage; biology; macrophage survival ... See more keywords
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Abstract B026: PIM kinases regulates tumor associated macrophage survival and inflammatory signaling

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.prca2023-b026

Abstract: Prostate tumors are highly infiltrated by immunosuppressive tumor associated macrophages (TAMs). TAMs secrete various factors that promote tumor progression and suppress antitumor immunity, making them a promising therapeutic target. PIM kinases are serine/threonine kinases that… read more here.

Keywords: pim kinases; pim; macrophage survival; tumor ... See more keywords

Human iNKT Cells Modulate Macrophage Survival and Phenotype

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recommendations! Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10071723

Abstract: CD1d-restricted invariant Natural Killer T (iNKT) cells are unconventional innate-like T cells whose functions highly depend on the interactions they establish with other immune cells. Although extensive studies have been reported on the communication between… read more here.

Keywords: inkt; survival phenotype; human inkt; macrophage survival ... See more keywords