Macrophage‐Targeted Efferocytosis Therapy Promotes Diabetic Wound Healing via Cellular Level Debridement
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202503035
Abstract: Impaired efferocytosis in diabetic wounds contributes to apoptotic cell accumulation, chronic inflammation, and poor healing outcomes. In this study, a multi‐hierarchical hydrogel designed to facilitate cellular debridement and initiate a healing process in diabetic wounds… read more here.
Keywords: therapy; wound healing; macrophage targeted; efferocytosis ... See more keywords
Macrophage-targeted and clearable glutathione-based MRI nanoprobes for atherosclerosis molecular imaging
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-019-4688-x
Abstract: Foam macrophage infiltration is one of the clinical features of high-risk atherosclerotic plaques. Many imaging modalities such as magnetic resonance imaging (MRI) have been used to detect foam macrophages for evaluating plaque vulnerability. However, targeting… read more here.
Keywords: macrophage targeted; imaging; mri; macrophage ... See more keywords
Entrapping of Nanoparticles in Yeast Cell Wall Microparticles for Macrophage-Targeted Oral Delivery of Cabazitaxel.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00357
Abstract: In this work, a nano-in-micro carrier was constructed by loading polymer-lipid hybrid nanoparticles (NPs) into porous and hollow yeast cell wall microparticles (YPs) for macrophage-targeted oral delivery of cabazitaxel (CTX). The YPs, primarily composed of… read more here.
Keywords: delivery; macrophage targeted; wall microparticles; targeted oral ... See more keywords
Red blood cell-derived nanovesicles for safe and efficient macrophage-targeted drug delivery in vivo.
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DOI: 10.1039/c8bm01258j
Abstract: Macrophage-targeted drug delivery has great therapeutic potential for the treatment of cancers and inflammatory diseases. There is also an unmet need for efficient and nontoxic means of in vivo macrophage depletion to determine the role… read more here.
Keywords: drug delivery; macrophage targeted; drug; targeted drug ... See more keywords
Macrophage-Targeted Nanomedicine for the Treatment of Atherosclerosis
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DOI: 10.2147/ijn.s529988
Abstract: Abstract Cardiovascular and cerebrovascular diseases are the leading causes of mortality worldwide, with atherosclerosis being the primary etiology. Despite its prevalence, atherosclerosis remains inadequately controlled by conventional therapeutic interventions. The unique physicochemical properties of nanomedicine… read more here.
Keywords: treatment; atherosclerosis; targeted nanomedicine; macrophage targeted ... See more keywords
Dry Powder Comprised of Isoniazid-Loaded Nanoparticles of Hyaluronic Acid in Conjugation with Mannose-Anchored Chitosan for Macrophage-Targeted Pulmonary Administration in Tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14081543
Abstract: Marketed dosage forms fail to deliver anti-tubercular drugs directly to the lungs in pulmonary Tuberculosis (TB). Therefore, nanomediated isoniazid (INH)-loaded dry powder for inhalation (Nano-DPI) was developed for macrophage-targeted delivery in TB. Mannosylated chitosan (MC)… read more here.
Keywords: dry powder; tuberculosis; powder; hyaluronic acid ... See more keywords