Alternative macrophages in atherosclerosis: not always protective!
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Investigation"
DOI: 10.1172/jci120123
Abstract: Atherosclerosis is a chronic inflammatory disease of the vasculature that is initiated by cholesterol deposition into the arterial wall, which triggers the infiltration of immune and inflammatory cells, including monocytes and macrophages. As atherosclerotic plaques… read more here.
Keywords: always protective; macrophages atherosclerosis; alternative macrophages; atherosclerosis always ... See more keywords
Targeting macrophages in atherosclerosis using nanocarriers loaded with liver X receptor agonists: A narrow review
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1147699
Abstract: Macrophages are involved in the whole process of atherosclerosis, which is characterized by accumulation of lipid and inflammation. Presently, clinically used lipid-lowering drugs cannot completely retard the progress of atherosclerosis. Liver X receptor (LXR) plays… read more here.
Keywords: lxr agonists; macrophages atherosclerosis; nanocarriers loaded; atherosclerosis ... See more keywords
Macrophages in Atherosclerosis, First or Second Row Players?
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9091214
Abstract: Macrophages represent a cell type that has been widely described in the context of atherosclerosis since the earliest studies in the 17th century. Their role has long been considered to be preponderant in the onset… read more here.
Keywords: atherosclerosis first; like cells; first second; macrophages atherosclerosis ... See more keywords
The Role of Macrophages in Atherosclerosis: Pathophysiologic Mechanisms and Treatment Considerations
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119568
Abstract: Atherosclerotic diseases are a leading cause of morbidity and mortality worldwide, despite the recent diagnostic and therapeutic advances. A thorough understanding of the pathophysiologic mechanisms is thus essential to improve the care of affected individuals.… read more here.
Keywords: pathophysiologic mechanisms; mechanisms treatment; atherosclerosis pathophysiologic; role ... See more keywords
Ironing out macrophages in atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2022196
Abstract: The most common cause of death worldwide is atherosclerosis and related cardiovascular disorders. Macrophages are important players in the pathogenesis of atherosclerosis and perform critical functions in iron homeostasis due to recycling iron by phagocytosis… read more here.
Keywords: macrophage iron; iron; atherosclerosis; ironing macrophages ... See more keywords