A Synthetic MUC1 Anticancer Vaccine Containing Mannose Ligands for Targeting Macrophages and Dendritic Cells
Sign Up to like & getrecommendations! Published in 2018 at "ChemMedChem"
DOI: 10.1002/cmdc.201700646
Abstract: A MUC1 anticancer vaccine equipped with covalently linked divalent mannose ligands was found to improve the antigen uptake and presentation by targeting mannose‐receptor‐positive macrophages and dendritic cells. It induced much stronger specific IgG immune responses… read more here.
Keywords: anticancer vaccine; mannose ligands; dendritic cells; macrophages dendritic ... See more keywords
IL-4/IL-13-mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury.
Sign Up to like & getrecommendations! Published in 2017 at "Kidney international"
DOI: 10.1016/j.kint.2016.08.020
Abstract: Cytokines IL-4 and IL-13 play important roles in polarization of macrophages/dendritic cells to an M2 phenotype, which is important for recovery from acute kidney injury. Both IL-4 and IL-13 activate JAK3/STAT6 signaling. In mice with… read more here.
Keywords: recovery; kidney injury; dendritic cells; macrophages dendritic ... See more keywords
An Accord of Nuclear Receptor Expression in M. tuberculosis Infected Macrophages and Dendritic Cells
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20769-4
Abstract: Mycobacterium tuberculosis instigates interactions with host factors to promote its survival within the host inimical conditions. Among such factors, nuclear receptors (NRs) seem to be promising candidates owing to their role in bacterial pathogenesis. However,… read more here.
Keywords: infection; tuberculosis; expression; macrophages dendritic ... See more keywords
SESLA suppresses the activation of macrophages and dendritic cells after Gram-positive bacterial challenge
Sign Up to like & getrecommendations! Published in 2022 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2022.2134790
Abstract: Abstract Background Secoeudesma sesquiterpenes lactone A (SESLA) is a sesquiterpene derived from Inula japonica Thunb. and is known to possess many pharmacological properties, e.g. anti-tumor and anti-inflammatory activities. However, the immunomodulatory role of SESLA in… read more here.
Keywords: macrophages dendritic; sesla; inflammatory; dendritic cells ... See more keywords
Targeted delivery to macrophages and dendritic cells by chemically modified mannose ligand-conjugated siRNA
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac308
Abstract: Abstract Extrahepatic delivery of small interfering RNAs (siRNAs) may have applications in the development of novel therapeutic approaches. However, reports on such approaches are limited, and the scarcity of reports concerning the systemically targeted delivery… read more here.
Keywords: macrophages dendritic; chemically modified; modified mannose; dendritic cells ... See more keywords
CCL17 Aggravates Myocardial Injury by Suppressing Recruitment of Regulatory T Cells
Sign Up to like & getrecommendations! Published in 2022 at "Circulation"
DOI: 10.1161/circulationaha.121.055888
Abstract: Supplemental Digital Content is available in the text. Background: Recent studies have established that CCR2 (C-C chemokine receptor type 2) marks proinflammatory subsets of monocytes, macrophages, and dendritic cells that contribute to adverse left ventricle… read more here.
Keywords: myocardial inflammation; ccl17; dendritic cells; macrophages dendritic ... See more keywords
Fungal-mediated lung allergic airway disease: The critical role of macrophages and dendritic cells
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010608
Abstract: Fungi are abundant in the environment, causing our lungs to be constantly exposed to a diverse range of species. While the majority of these are cleared effectively in healthy individuals, constant exposure to spores (especially… read more here.
Keywords: macrophages dendritic; role; lung; allergic inflammation ... See more keywords
The application of the natural killer cells, macrophages and dendritic cells in treating various types of cancer
Sign Up to like & getrecommendations! Published in 2020 at "Physical sciences reviews"
DOI: 10.1515/psr-2019-0058
Abstract: Innate immune cells such as natural killer (NK) cells, macrophages and dendritic cells (DCs) are involved in the surveillance and clearance of tumor. Intensive research has exposed the mechanisms of recognition and elimination of tumor… read more here.
Keywords: cells macrophages; natural killer; dendritic cells; macrophages dendritic ... See more keywords
Mechanosensing in macrophages and dendritic cells in steady-state and disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1044729
Abstract: Macrophages and dendritic cells are myeloid cells that play critical roles in immune responses. Macrophages help to maintain homeostasis through tissue regeneration and the clearance of dead cells, but also mediate inflammatory processes against invading… read more here.
Keywords: macrophages dendritic; cell; disease; dendritic cells ... See more keywords
Distinct Transcriptional Profile of PDZ Genes after Activation of Human Macrophages and Dendritic Cells
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DOI: 10.3390/ijms23137010
Abstract: The PDZ (PSD95, Dlg and ZO-1) genes encode proteins that primarily function as scaffolds of diverse signaling pathways. To date, 153 PDZ genes have been identified in the human genome, most of which have multiple… read more here.
Keywords: macrophages dendritic; pdz; dendritic cells; human macrophages ... See more keywords
Effects of mimicked acetylated HMGB1 on macrophages and dendritic cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2018.9584
Abstract: Extracellular high mobility group box 1 (HMGB1) serves a critical role in inflammatory diseases. HMGB1 is released into the extracellular environment mainly by passive release from necrotic cells or active secretion from monocytes/macrophages following stimulation.… read more here.
Keywords: hmgb1; acetylated hmgb1; present study; dendritic cells ... See more keywords