Tumor-associated microglia and macrophages in glioblastoma: From basic insights to therapeutic opportunities
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DOI: 10.3389/fimmu.2022.964898
Abstract: Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults. Currently, the standard treatment of glioblastoma includes surgery, radiotherapy, and chemotherapy. Despite aggressive treatment, the median survival is only 15 months. GBM… read more here.
Keywords: associated microglia; glioblastoma basic; macrophages glioblastoma; microglia macrophages ... See more keywords
Macrophages in Glioblastoma Development and Therapy: A Double-Edged Sword
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DOI: 10.3390/life12081225
Abstract: Glioblastoma (GBM) is one of the leading lethal tumors, featuring aggressive malignancy and poor outcome to current standard temozolomide (TMZ) or radio-based therapy. Developing immunotherapies, especially immune checkpoint inhibitors, have improved patient outcomes in other… read more here.
Keywords: macrophages glioblastoma; therapy; development therapy; glioblastoma development ... See more keywords