Macrophages-induced IL-18–mediated eosinophilia promotes characteristics of pancreatic malignancy
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DOI: 10.26508/lsa.202000979
Abstract: The current study presents first CP murine model that show IL-18–induced eosinophil inflammation-mediated induction of oncogenic proteins and several pathological malignant characteristics. Reports indicate that accumulated macrophages in the pancreas are responsible for promoting the… read more here.
Keywords: characteristics pancreatic; macrophages induced; pancreatic malignancy; murine model ... See more keywords
Proline metabolism reprogramming of trained macrophages induced by early respiratory infection combined with allergen sensitization contributes to development of allergic asthma in childhood of mice
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DOI: 10.3389/fimmu.2022.977235
Abstract: Background Infants with respiratory syncytial virus (RSV)-associated bronchiolitis are at increased risk of childhood asthma. Recent studies demonstrated that certain infections induce innate immune memory (also termed trained immunity), especially in macrophages, to respond more… read more here.
Keywords: asthma childhood; trained macrophages; allergic asthma; infection ... See more keywords
Induction of unique macrophage subset by simultaneous stimulation with LPS and IL-4
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DOI: 10.3389/fimmu.2023.1111729
Abstract: Macrophages manifest as various subtypes that play diverse and important roles in immunosurveillance and the maintenance of immunological homeostasis in various tissues. Many in vitro studies divide macrophages into two broad groups: M1 macrophages induced… read more here.
Keywords: simultaneous stimulation; induced macrophages; lps induced; stimulation lps ... See more keywords