Articles with "macrophages inhibit" as a keyword



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Macrophages inhibit Coxiella burnetii by the ACOD1‐itaconate pathway for containment of Q fever

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Published in 2022 at "EMBO Molecular Medicine"

DOI: 10.15252/emmm.202215931

Abstract: Infection with the intracellular bacterium Coxiella (C.) burnetii can cause chronic Q fever with severe complications and limited treatment options. Here, we identify the enzyme cis- aconitate decarboxylase 1 (ACOD1 or IRG1) and its product… read more here.

Keywords: macrophages inhibit; itaconate; fever; coxiella burnetii ... See more keywords