JAK2V617F Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages
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DOI: 10.3389/fimmu.2020.589048
Abstract: A substitution mutation of valine to phenylalanine at codon encoding position 617 of the Janus kinase 2 (JAK2) gene (JAK2V617F ) has been detected in myeloid cells of some individuals with higher levels of proinflammatory… read more here.
Keywords: stabilization; production; jak2v617f mutation; macrophages jak2v617f ... See more keywords