The modulatory effects of the PDE4 inhibitors CHF6001 and roflumilast in alveolar macrophages and lung tissue from COPD patients.
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DOI: 10.1016/j.cyto.2019.154739
Abstract: BACKGROUND We compared the anti-inflammatory effects of phosphodiesterase type 4 (PDE4) inhibitor roflumilast with CHF6001, a novel PDE4 inhibitor designed for inhaled administration, using human alveolar macrophages (AM) and lung tissue explants models. METHODS AM… read more here.
Keywords: macrophages lung; tissue; lung tissue; copd patients ... See more keywords