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M1 Macrophages but Not M2 Macrophages Are Characterized by Upregulation of CRP Expression via Activation of NFκB: a Possible Role for Ox-LDL in Macrophage Polarization

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Published in 2018 at "Inflammation"

DOI: 10.1007/s10753-018-0793-8

Abstract: Arterial macrophages comprise a heterogeneous population: pro-inflammatory (M1) and anti-inflammatory (M2). Since C-reactive protein (CRP) is produced by macrophages in atherosclerotic lesions, understanding of CRP regulation in macrophages could be crucial to decipher inflammatory patterns… read more here.

Keywords: ldl; crp expression; macrophages macrophages; expression ... See more keywords