17β-estradiol modulates the expression of hormonal receptors on THP-1 T. gondii-infected macrophages and monocytes in an AKT and ERK-dependent manner.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2021.111433
Abstract: Toxoplasma gondii (T. gondii) is a parasite common in pregnancy. Monocytes and macrophages are a significant immunologic barrier against T. gondii by boosting up inflammation. This outcome is highly regulated by signaling pathways such as… read more here.
Keywords: expression hormonal; gondii infected; hormonal receptors; gondii ... See more keywords
α-Mangostin Inhibited M1 Polarization of Macrophages/Monocytes in Antigen-Induced Arthritis Mice by Up-Regulating Silent Information Regulator 1 and Peroxisome Proliferators-Activated Receptor γ Simultaneously
Sign Up to like & getrecommendations! Published in 2023 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s397914
Abstract: Background α-Mangostin (MG) showed the potentials in alleviating experimental arthritis, inhibiting inflammatory polarization of macrophages/monocytes, and regulating peroxisome proliferators-activated receptor γ (PPAR-γ) and silent information regulator 1 (SIRT1) signals. The aim of this study was… read more here.
Keywords: macrophages monocytes; ppar; sirt1 ppar; polarization macrophages ... See more keywords
Dynamic CD8+ T Cell Cooperation with Macrophages and Monocytes for Successful Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14143546
Abstract: Simple Summary Innate and adaptive immunity mutually regulate one another in a dynamic fashion during immune responses. In infectious contexts, positive interactions between macrophages, monocytes and T cells are well recognized, but this is not… read more here.
Keywords: immunotherapy; cd8 cell; macrophages monocytes; cooperation ... See more keywords
SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of immunology"
DOI: 10.4049/jimmunol.2300110
Abstract: SARS-CoV-2 has caused an estimated 7 million deaths worldwide to date. A secreted SARS-CoV-2 accessory protein, known as open reading frame 8 (ORF8), elicits inflammatory pulmonary cytokine responses and is associated with disease severity in… read more here.
Keywords: orf8 mediates; cov orf8; macrophages monocytes; sars cov ... See more keywords
Mesenchymal Stem Cells Attenuate Asthmatic Inflammation and Airway Remodeling by Modulating Macrophages/Monocytes in the IL-13-Overexpressing Mouse Model
Sign Up to like & getrecommendations! Published in 2022 at "Immune Network"
DOI: 10.4110/in.2022.22.e40
Abstract: Mesenchymal stem cells (MSCs) are attractive alternatives to conventional anti-asthmatic drugs for severe asthma. Mechanisms underlying the anti-asthmatic effects of MSCs have not yet been elucidated. This study evaluated the anti-asthmatic effects of intravenously administered… read more here.
Keywords: inflammation; inflammation airway; mesenchymal stem; mscs ... See more keywords