Characterization of Macrophages and Myofibroblasts Appearing in Dibutyltin Dichloride–Induced Rat Pancreatic Fibrosis
Sign Up to like & getrecommendations! Published in 2020 at "Toxicologic Pathology"
DOI: 10.1177/0192623319893310
Abstract: Macrophages and myofibroblasts are important in fibrogenesis. The cellular characteristics in pancreatic fibrosis remain to be investigated. Pancreatic fibrosis was induced in F344 rats by a single intravenous injection of dibutyltin dichloride. Histopathologically, the induced… read more here.
Keywords: fibrosis; dibutyltin dichloride; macrophages myofibroblasts; mesenchymal cells ... See more keywords
Transformation of macrophages into myofibroblasts in fibrosis-related diseases: emerging biological concepts and potential mechanism
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1474688
Abstract: Macrophage-myofibroblast transformation (MMT) transforms macrophages into myofibroblasts in a specific inflammation or injury microenvironment. MMT is an essential biological process in fibrosis-related diseases involving the lung, heart, kidney, liver, skeletal muscle, and other organs and… read more here.
Keywords: related diseases; macrophages myofibroblasts; fibrosis related; mechanism ... See more keywords