A novel chrysin thiazole derivative polarizes macrophages to an M1 phenotype via targeting TLR4.
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DOI: 10.1016/j.intimp.2020.106986
Abstract: Tumor-associated macrophages (TAMs) are an important cause of tumorigenesis and tumor development. M2 macrophages can promote tumor growth while M1 macrophages kill tumor cells, therefore, polarizing macrophages to achieve a functional M1 phenotype could effectively… read more here.
Keywords: macrophages phenotype; tumor; tlr4; chr ... See more keywords