TSPO ligand Ro5-4864 modulates microglia/macrophages polarization after subarachnoid hemorrhage in mice
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.134977
Abstract: Brain injury after subarachnoid hemorrhage (SAH) is closely related to microglia/macrophages-induced neuroinflammation. Translocator protein (TSPO) is a hall marker of activated microglia/macrophages, and the TSPO ligands have been proved to be beneficial for controlling neuroinflammation.… read more here.
Keywords: macrophages polarization; ro5 4864; subarachnoid hemorrhage; tspo ligand ... See more keywords
Suppression of the hyaluronic acid pathway induces M1 macrophages polarization via STAT1 in glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Cell Death Discovery"
DOI: 10.1038/s41420-022-00973-y
Abstract: Immunosuppressive tumor microenvironment is a crucial factor that impedes the success of tumor immunotherapy, and tumor-associated macrophages (TAMs) are essential for the formation of tumor immunosuppressive microenvironment. Hyaluronic acid (HA) is highly important brick for… read more here.
Keywords: glioblastoma; macrophages polarization; microenvironment; tumor ... See more keywords
Knockdown of lncRNA PCAT6 suppresses the growth of non-small cell lung cancer cells by inhibiting macrophages M2 polarization via miR-326/KLF1 axis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2076388
Abstract: ABSTRACT Non-small cell lung cancer (NSCLC) is the most common malignant tumor of lung, which seriously threatens the life of people. It has been reported that lncRNA prostate cancer-associated transcript 6 (PCAT6) could facilitate the… read more here.
Keywords: macrophages polarization; pcat6; nsclc cells; 326 klf1 ... See more keywords
Urine Macrophages Polarization Predicts Renal Function Recovery after Nephron-Sparing Surgery in Patients with Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Urologia Internationalis"
DOI: 10.1159/000525789
Abstract: Introduction: This study was conducted to investigate the underlying associations between urine macrophages polarization and renal function recovery after nephron-sparing surgery (NSS) in patients with renal cell carcinoma (RCC) and to explore the potential application… read more here.
Keywords: function recovery; macrophages polarization; urine macrophages; renal function ... See more keywords
Cyclosporine A Regulates Influenza A Virus-induced Macrophages Polarization and Inflammatory Responses by Targeting Cyclophilin A
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.861292
Abstract: Cyclosporine A (CsA) is an immunosuppressive drug that suppresses T cell responses and is broadly used in transplantation. Its immunosuppressive action is closely linked to its binding of cyclophilin A (CypA), which widely distributed in… read more here.
Keywords: inflammatory responses; polarization inflammatory; macrophages polarization; csa ... See more keywords
The imbalance of liver resident macrophages polarization promotes chronic autoimmune hepatitis development in mice
Sign Up to like & getrecommendations! Published in 2023 at "PeerJ"
DOI: 10.7717/peerj.14871
Abstract: Background Autoimmune hepatitis (AIH) is a chronic immune-mediated inflammatory liver disease. At present, it is largely unknown how the innate immune cells influence AIH development. Objective To inquiry about mechanism of liver resident macrophages in… read more here.
Keywords: development; macrophages polarization; resident macrophages; liver resident ... See more keywords