Decidual stromal cells support tolerance at the human foetal-maternal interface by inducing regulatory M2 macrophages and regulatory T-cells.
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DOI: 10.1016/j.jri.2021.103330
Abstract: During pregnancy, the semi-allogeneic nature of the foetus requires maternal immune adaption and acquisition of tolerance at the foetal-maternal interface. Macrophages with regulatory properties and regulatory T (Treg) cells are central in promoting foetal tolerance… read more here.
Keywords: tolerance; stromal cells; maternal interface; macrophages regulatory ... See more keywords