Yeast‐mediated mRNA delivery polarizes immuno‐suppressive macrophages towards an immuno‐stimulatory phenotype
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DOI: 10.1016/j.ejpb.2017.03.008
Abstract: Graphical abstract Figure. No caption available. ABSTRACT Macrophages have increasingly gained interest as a therapeutic target since they represent an integral component of the tumor microenvironment. In fact, M2 macrophage accumulation in solid tumors is… read more here.
Keywords: phenotype; yeast mediated; delivery; macrophages towards ... See more keywords
Neutrophils orchestrate post-myocardial infarction healing by polarizing macrophages towards a reparative phenotype
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DOI: 10.1093/eurheartj/ehw002
Abstract: Aims Acute myocardial infarction (MI) is the leading cause of mortality worldwide. Anti-inflammatory strategies to reduce neutrophil-driven acute post-MI injury have been shown to limit acute cardiac tissue damage. On the other hand, whether neutrophils… read more here.
Keywords: towards reparative; depleted mice; myocardial infarction; polarizing macrophages ... See more keywords