Tumour-associated macrophages as treatment targets in oncology
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Clinical Oncology"
DOI: 10.1038/nrclinonc.2016.217
Abstract: Macrophages are crucial drivers of tumour-promoting inflammation. Tumour-associated macrophages (TAMs) contribute to tumour progression at different levels: by promoting genetic instability, nurturing cancer stem cells, supporting metastasis, and taming protective adaptive immunity. TAMs can exert… read more here.
Keywords: treatment targets; tumour associated; oncology tumour; macrophages treatment ... See more keywords
Immunoregulation of synovial macrophages for the treatment of osteoarthritis
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DOI: 10.1515/biol-2022-0567
Abstract: Abstract Osteoarthritis (OA) is the most common joint disease affecting approximately 10% of men and 18% of women older than 60. Its pathogenesis is still not fully understood; however, emerging evidence has suggested that chronic… read more here.
Keywords: treatment osteoarthritis; macrophages treatment; immunoregulation synovial; synovial macrophages ... See more keywords
Engineered M2a macrophages for the treatment of osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1054938
Abstract: Background Macrophage is a central regulator of innate immunity. Its M2 subsets, such as interstitial synovial macrophages, have been found to play critical roles in suppressing chronic inflammation and maintaining homeostasis within the joint. These… read more here.
Keywords: engineered m2a; osteoarthritis; m2a macrophages; anti inflammatory ... See more keywords