Macrophages from xCT-deficient mice survive under low cysteine/glutathione redox conditions with high oxidative stress
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DOI: 10.1016/j.freeradbiomed.2017.04.186
Abstract: Murine macrophages produce a large body of reactive oxygen species and nitric oxide (NO) in response to inflammatory stimuli and confer protection against bacterial infection. xCT transports cystine into cells in combination with glutamate discharge… read more here.
Keywords: macrophages xct; xct deficient; mice survive; xct macrophages ... See more keywords