Gold Nanoparticles Inhibit Macropinocytosis by Decreasing KRAS Activation.
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DOI: 10.1021/acsnano.3c00920
Abstract: The RAS-transformed cells utilize macropinocytosis to acquire amino acids to support their uncontrolled growth. However, targeting RAS to inhibit macropinocytosis remains a challenge. Here, we report that gold nanoparticles (GNP) inhibit macropinocytosis by decreasing KRAS… read more here.
Keywords: inhibit macropinocytosis; macropinocytosis decreasing; gold nanoparticles; kras activation ... See more keywords