Toxicologic evaluation of repetitive 4‐week intravenous injections of midkine antisense oligonucleotide nanoliposomes in rats
Sign Up to like & getrecommendations! Published in 2019 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2019.01.030
Abstract: Abstract Midkine antisense oligonucleotide (MK‐ASODN) nanoliposomes have previously been shown to have inhibitory activity against hepatocellular carcinoma growth. Herein we report the 4‐week sub‐chronic toxicity of MK‐ASODN nanoliposomes in SD rats. The adverse effects included… read more here.
Keywords: week; asodn nanoliposomes; nanoliposomes rats; midkine antisense ... See more keywords
Imaging of Gut Bacterial Macroscopic Changes in Simulated Microgravity-Exposed Rats via In Vivo Metabolic Labeling.
Sign Up to like & getrecommendations! Published in 2024 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c05028
Abstract: The impact of the microgravity environment on gut bacteria has been widely recognized to induce notable gastrointestinal pathology during extended spaceflight. However, most current studies for gut microbiome homeostasis profiling are based on the 16S… read more here.
Keywords: chemistry; macroscopic changes; pathology; gut bacterial ... See more keywords