Prevention and treatment of age‐related macular degeneration
Sign Up to like & getrecommendations! Published in 2017 at "Prescriber"
DOI: 10.1002/psb.1533
Abstract: Age-related macular degeneration (AMD) is a degenerative change of the central area of the retina (macula) in people aged 55 years and above and is the leading cause of irreversible sight loss in the developed… read more here.
Keywords: related macular; treatment; macular degeneration; age related ... See more keywords
Making Biological Sense of Genetic Studies of Age-Related Macular Degeneration.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-66014-7_8
Abstract: Age-related macular degeneration (AMD) is a major cause of blindness in older individuals worldwide. The disease is characterized by deposition of drusen between the retinal pigment epithelium (RPE) and Bruch's membrane, RPE atrophy and death… read more here.
Keywords: related macular; macular degeneration; disease; age related ... See more keywords
Pleiotropic Effects of Risk Factors in Age-Related Macular Degeneration and Seemingly Unrelated Complex Diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-75402-4_30
Abstract: Age-related macular degeneration (AMD) is a complex disease with both environmental and genetic factors influencing disease risk. Genome-wide case-control association studies, candidate gene analyses, and epidemiological studies reinforced the notion that AMD is predominantly a… read more here.
Keywords: risk; macular degeneration; age related; related macular ... See more keywords
MicroRNA as Therapeutics for Age-Related Macular Degeneration.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-75402-4_5
Abstract: MicroRNA (miRNA) are a class of endogenously expressed small non-coding RNA molecules that function by repressing or silencing post-transcriptional gene expression. While miRNAs were only identified in humans as recently as the turn of this… read more here.
Keywords: related macular; macular degeneration; microrna therapeutics; age related ... See more keywords
Anaphylatoxin Signaling in Retinal Pigment and Choroidal Endothelial Cells: Characteristics and Relevance to Age-Related Macular Degeneration.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-75402-4_6
Abstract: Age-related macular degeneration (AMD) is the leading cause of blindness in the USA. Polymorphisms in various complement components are associated with an increased risk for AMD, and it has been hypothesized that an overactive complement… read more here.
Keywords: macular degeneration; age related; related macular; pathology ... See more keywords
Introduction to the multi-author review on macular degeneration
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03418-5
Abstract: Prolonged life expectancies contribute to the increasing prevalence of age-related macular degeneration (AMD) that is already the leading cause of severe vision loss among the elderly in developed countries. In dry AMD, the disease culminates… read more here.
Keywords: author review; macular degeneration; multi author;
Plasma levels of hypoxia-regulated factors in patients with age-related macular degeneration
Sign Up to like & getrecommendations! Published in 2017 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-017-3846-z
Abstract: PurposeVarious hypoxia-related proteins are differentially expressed in the retina and secreted to the vitreous and/or aqueous humor of patients affected by dry or neovascular age-related macular degeneration (nAMD). To determine whether these conditions alter concentrations… read more here.
Keywords: macular degeneration; age related; related macular; age ... See more keywords
Increased choroidal thickness: a new feature to monitor age-related macular degeneration recurrence
Sign Up to like & getrecommendations! Published in 2018 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-018-04216-8
Abstract: PurposeThe main objective of this study was to assess choroidal thickness (CT) changes during an exudative recurrence of age-related macular degeneration (AMD).MethodsA real-life prospective non-interventional 9-month study was conducted in two centers in consecutive patients… read more here.
Keywords: macular degeneration; recurrence; age related; related macular ... See more keywords
Association of imaging biomarkers and local activation of complement in aqueous humor of patients with early forms of age-related macular degeneration
Sign Up to like & getrecommendations! Published in 2020 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-020-04910-6
Abstract: To investigate a possible correlation between established imaging biomarkers for age-related macular degeneration and local complement system activation, measured in aqueous humor (AH) of patients with early stages of age-related macular degeneration (AMD) and controls.… read more here.
Keywords: imaging biomarkers; macular degeneration; age related; related macular ... See more keywords
Switching from aflibercept to brolucizumab for the treatment of refractory neovascular age-related macular degeneration
Sign Up to like & getrecommendations! Published in 2022 at "Japanese Journal of Ophthalmology"
DOI: 10.1007/s10384-022-00908-1
Abstract: To examine the 16-week outcomes of switching to brolucizumab in eyes with neovascular age-related macular degeneration (nAMD) refractory to aflibercept. Retrospective observational study. Data of eyes with nAMD who switched to brolucizumab because of resistance… read more here.
Keywords: refractory; age related; macular degeneration; treatment ... See more keywords
An epidemiological investigation of age-related macular degeneration in aged population in China: the Hainan study
Sign Up to like & getrecommendations! Published in 2017 at "International Ophthalmology"
DOI: 10.1007/s10792-017-0639-7
Abstract: PurposeThe aim of this study was to investigate the prevalence of age-related macular degeneration (AMD) and the risk factors in the residents aged ≥50 years in Hainan Province.MethodsRandom sampling was carried out in four separated cities… read more here.
Keywords: macular degeneration; age related; related macular; age ... See more keywords