Involvement of AMPK in regulating the degradation of MAD2B under high glucose in neuronal cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13046
Abstract: Although our recent study has demonstrated that mitotic spindle assembly checkpoint protein (MAD2B) mediates high glucose‐induced neuronal apoptosis, the mechanisms for MAD2B degradation under hyperglycaemia have not yet been elucidated. In this study, we first… read more here.
Keywords: degradation; mad2b; activation ampk; high glucose ... See more keywords
Conditional deletion of MAD2B in forebrain neurons enhances hippocampus-dependent learning and memory in mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.956029
Abstract: Mitotic arrest deficient 2-like protein 2 (MAD2B) is not only a DNA damage repair agent but also a cell cycle regulator that is widely expressed in the hippocampus and the cerebral cortex. However, the functions… read more here.
Keywords: cko mice; mad2b; mice; mad2b cko ... See more keywords