Bile Acids Modulate Colonic MAdCAM-1 Expression in a Murine Model of Combined Cholestasis and Colitis
Sign Up to like & getrecommendations! Published in 2020 at "Mucosal immunology"
DOI: 10.1038/s41385-020-00347-6
Abstract: Primary sclerosing cholangitis (PSC) is a progressive fibrosing cholestatic liver disease that is strongly associated with inflammatory bowel disease (IBD). PSC-associated IBD (PSC-IBD) displays a unique phenotype characterized by right-side predominant colon inflammation and increased… read more here.
Keywords: psc ibd; psc; madcam expression; colitis ... See more keywords
Colonic Tissue Expression of MAdCAM‐1 Is Not Predictive of Vedolizumab Responsiveness in Inflammatory Bowel Disease
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DOI: 10.1111/cts.70422
Abstract: We assessed the predictive value of MAdCAM‐1 expression on response to vedolizumab in patients with inflammatory bowel disease. This was a retrospective, single‐center, cohort study including 109 patients with pretreatment inflammation who completed at least… read more here.
Keywords: madcam expression; vedolizumab; bowel disease; expression ... See more keywords