Maduramicin induces cardiotoxicity via Rac1 signaling‐independent methuosis in H9c2 cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4175
Abstract: Maduramicin frequently induces severe cardiotoxicity in target and nontarget animals in clinic. Apoptotic and non‐apoptotic cell death mediate its cardiotoxicity; however, the underlying non‐apoptotic cell death induced by maduramicin remains unclear. In current study, a… read more here.
Keywords: h9c2 cells; cardiotoxicity; h9c2; methuosis ... See more keywords
Long circulatory liposomal maduramicin inhibits the growth of Plasmodium falciparum blood stages in culture and cures murine models of experimental malaria.
Sign Up to like & getrecommendations! Published in 2018 at "Nanoscale"
DOI: 10.1039/c8nr02442a
Abstract: Malaria continues to be one of the deadliest infectious diseases and a global health menace. The emergence and spread of drug-resistant strains of malaria parasites have further made the process of disease management grimmer. Thus,… read more here.
Keywords: murine models; liposomal maduramicin; blood stages; long circulatory ... See more keywords