Articles with "maf driven" as a keyword



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Abstract 3681: c-MAF-driven metabolic reprogramming mediates H3K27 hyperacetylation to regulate super enhancer-associated genes

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-3681

Abstract: Overexpression of transcription factor c-MAF is found in about 50% of multiple myeloma cases, and associated with the prognostically unfavorable t(14;16) translocation subtype. Genetic alterations can modify the epigenome through metabolite availability that act as… read more here.

Keywords: metabolic reprogramming; maf; reprogramming mediates; driven metabolic ... See more keywords