MAF1 is a chronic repressor of RNA polymerase III transcription in the mouse
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68665-0
Abstract: Maf1−/− mice are lean, obesity-resistant and metabolically inefficient. Their increased energy expenditure is thought to be driven by a futile RNA cycle that reprograms metabolism to meet an increased demand for nucleotides stemming from the… read more here.
Keywords: pol iii; maf1; iii transcription; rna polymerase ... See more keywords
Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkad063
Abstract: Abstract Inorganic phosphate is an essential nutrient acquired by cells from their environment. Here, we characterize the adaptative responses of fission yeast to chronic phosphate starvation, during which cells enter a state of quiescence, initially… read more here.
Keywords: phosphate; trna biogenesis; maf1; starvation ... See more keywords
A Toxoplasma Gondii Locus Required for the Direct Manipulation of Host Mitochondria Has Maintained Multiple Ancestral Functions
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Microbiology"
DOI: 10.2210/pdb6bxt/pdb
Abstract: The Toxoplasma gondii locus mitochondrial association factor 1 (MAF1) encodes multiple paralogs, some of which mediate host mitochondrial association (HMA). Previous work showed that HMA was a trait that arose in T. gondii through neofunctionalization… read more here.
Keywords: gondii locus; ancestral functions; host mitochondria; maf1 ... See more keywords