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   Articles with "maff" as a keyword



The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling

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recommendations! Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-24631-6

Abstract: Hypoxia plays a critical role in tumor progression including invasion and metastasis. To determine critical genes regulated by hypoxia that promote invasion and metastasis, we screen fifty hypoxia inducible genes for their effects on invasion.… read more here.

Keywords: maff; invasion; il11; stat3 ... See more keywords

ZNF655 promotes tumor growth and chemoresistance by targeting MAFF-CCND1 axis in ovarian cancer

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recommendations! Published in 2025 at "Cancer Cell International"

DOI: 10.1186/s12935-025-03997-3

Abstract: Ovarian cancer (OC) has the highest mortality rate among gynecological malignancies. The role of zinc finger protein 655 (ZNF655) in cancer progression has been highlighted but remains unclear and needs further exploration. In this study,… read more here.

Keywords: ccnd1; cancer; chemoresistance; ovarian cancer ... See more keywords

Involvement of MAFB and MAFF in Retinoid-Mediated Suppression of Hepatocellular Carcinoma Invasion

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recommendations! Published in 2018 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms19051450

Abstract: Retinoids exert antitumor effects through the retinoic acid receptor α (RARα). In the present study, we sought to identify the factors involved in the RARα-mediated transcriptional regulation of the tumor suppressor gene and the tissue… read more here.

Keywords: hepatocellular carcinoma; maff; invasion; mediated suppression ... See more keywords

MAFF inhibits angiogenesis in non-small cell lung cancer by suppressing YAP1 nuclear translocation

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recommendations! Published in 2025 at "PeerJ"

DOI: 10.7717/peerj.20395

Abstract: Objective To investigate the roles of MAFF and Yes-associated protein 1 (YAP1) in regulating angiogenesis in non-small cell lung cancer (NSCLC) and to explore the mechanism through which MAFF inhibits angiogenesis by suppressing YAP1 nuclear… read more here.

Keywords: angiogenesis; maff; yap1 nuclear; nuclear translocation ... See more keywords