The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
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DOI: 10.1038/s41467-021-24631-6
Abstract: Hypoxia plays a critical role in tumor progression including invasion and metastasis. To determine critical genes regulated by hypoxia that promote invasion and metastasis, we screen fifty hypoxia inducible genes for their effects on invasion.… read more here.
Keywords: maff; invasion; il11; stat3 ... See more keywords
Involvement of MAFB and MAFF in Retinoid-Mediated Suppression of Hepatocellular Carcinoma Invasion
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DOI: 10.3390/ijms19051450
Abstract: Retinoids exert antitumor effects through the retinoic acid receptor α (RARα). In the present study, we sought to identify the factors involved in the RARα-mediated transcriptional regulation of the tumor suppressor gene and the tissue… read more here.
Keywords: hepatocellular carcinoma; maff; invasion; mediated suppression ... See more keywords