Knockdown of MAGE‐A6 enhanced the irradiation sensitivity of non‐small cell lung cancer cells by activating the AMPK pathway
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23519
Abstract: Non‐small cell lung cancer is a common respiratory tumor. The mortality rate of lung cancer patients has continued to rise in recent years. Several studies revealed that the expression of melanoma antigen 6 (MAGE‐A6) promoted… read more here.
Keywords: lung cancer; non small; small cell; mage ... See more keywords
Suppression of MAGE-A10 alters the metastatic phenotype of tongue squamous cell carcinoma cells
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2017.04.009
Abstract: MAGE-A10 is a member of the MAGE protein family (melanoma associated antigen) which is overexpressed in cancer cells. Although MAGE-A10 has been characterized for some time and is generally associated to metastasis its function remains… read more here.
Keywords: cell carcinoma; squamous cell; mage; mage a10 ... See more keywords
Relationship between glucose variability evaluated by continuous glucose monitoring and clinical factors, including glucagon-stimulated insulin secretion in patients with type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2019.107904
Abstract: AIMS To evaluate the clinical factors affecting daily and day-to-day glucose variability by using continuous glucose monitoring. METHODS We performed a cross-sectional analysis of patients with type 2 diabetes mellitus (T2DM) who underwent a glucagon… read more here.
Keywords: mage; clinical factors; variability; glucose variability ... See more keywords
Multi-dynamic modelling reveals strongly time-varying resting fMRI correlations
Sign Up to like & getrecommendations! Published in 2022 at "Medical Image Analysis"
DOI: 10.1016/j.media.2022.102366
Abstract: Highlights • MAGE is multi-dynamic in that it models temporal fluctuations in FC independently from fluctuations in the mean of the activity.• MAGE reveals stronger changes in FC over time than single-dynamic approaches, such as… read more here.
Keywords: time; multi dynamic; time varying; dynamic modelling ... See more keywords
Executive function, repetitive behaviour and restricted interests in neurodevelopmental disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Research in developmental disabilities"
DOI: 10.1016/j.ridd.2021.104166
Abstract: BACKGROUND Individuals with genetic syndromes show unique profiles of repetitive behaviours and restricted interests (RRBs). The executive dysfunction account of RRBs suggests that in autistic (AUT) individuals executive function impairments underpin RRBs, but not communication… read more here.
Keywords: restricted interests; function; aut individuals; function repetitive ... See more keywords
Discovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00185
Abstract: MAGE proteins are cancer testis antigens (CTAs) that are characterized by highly conserved MAGE homology domains (MHDs) and are increasingly being found to play pivotal roles in promoting aggressive cancer types. MAGE-A4, in particular, increases… read more here.
Keywords: mage rad18; potent; mage; discovery structural ... See more keywords
Involvement of NY-ESO-1 and MAGE-A4 in the pathogenesis of desmoid tumors
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033908
Abstract: The involvement of New York esophageal squamous cell carcinoma-1 (NY-ESO-1) and melanoma-associated antigen A4 (MAGE-A4) in soft-tissue sarcoma pathogenesis has recently been reported; however, their involvement in desmoid tumors (DTs) remains unknown. This study aimed… read more here.
Keywords: desmoid tumors; positivity; mage; correlation ... See more keywords
Association of homogeneous inflamed gene signature with a better outcome in patients with metastatic melanoma treated with MAGE-A3 immunotherapeutic
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-000384
Abstract: Purpose This study assessed clinical activity, safety and immunogenicity of MAGE-A3 immunotherapeutic in patients with MAGE-A3-positive metastatic melanoma. Patients and methods In this open-label, multicentre, uncontrolled, Phase II study (ClinicalTrials.gov NCT00896480),patients received ≤24 doses of… read more here.
Keywords: mage immunotherapeutic; clinical activity; mage; treatment ... See more keywords
PO-341 The role of cancer/testis antigens from MAGE-A family and NY-ESO-1 in ductal carcinoma in situ (DCIS)
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.853
Abstract: Introduction Cancer/testis antigens (CTA) are a large family of tumor-associated antigens expressed in human tumours of different histological origin, but not in normal tissues except for testis and placenta. Several immunohistochemical studies confirmed the association… read more here.
Keywords: mage; testis antigens; family; cancer testis ... See more keywords
125 Reexamination of MAGE-A3 as a T-cell Therapeutic Target
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-sitc2020.0125
Abstract: Background Recurrent cancer-specific targets are rare. Given the pace of genomic research over the past three decades, few are likely to lie yet undiscovered. In 2013 an innovative MAGE-A3-directed cancer therapeutic of great potential value… read more here.
Keywords: cell therapeutic; mage; mage a12; target ... See more keywords
MAGE-Targeted Gold Nanoparticles for Ultrasound Imaging-Guided Phototherapy in Melanoma
Sign Up to like & getrecommendations! Published in 2020 at "BioMed Research International"
DOI: 10.1155/2020/6863231
Abstract: Gold nanorods exhibit a wide variety of applications such as tumor molecular imaging and photothermal therapy (PTT) due to their tunable optical properties. Several studies have demonstrated that the combination of other therapeutic strategies may… read more here.
Keywords: melanoma; ultrasound imaging; mage targeted; mage ... See more keywords