Expression of Cancer‐Testis Antigens MAGE‐A1, MAGE‐A4, NY‐ESO‐1 and PRAME in Bone and Soft Tissue Sarcomas: The Experience From a Single Center in China
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Medicine"
DOI: 10.1002/cam4.70750
Abstract: Sarcomas are a heterogeneous group of malignancies, low disease‐control levels and the limited durability of responses have prompted the exploration of various novel immunotherapeutic approaches. To preliminarily explore the feasibility of cancer vaccines based on… read more here.
Keywords: cancer; mage; sarcomas; expression ... See more keywords
Knockdown of MAGE‐A6 enhanced the irradiation sensitivity of non‐small cell lung cancer cells by activating the AMPK pathway
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23519
Abstract: Non‐small cell lung cancer is a common respiratory tumor. The mortality rate of lung cancer patients has continued to rise in recent years. Several studies revealed that the expression of melanoma antigen 6 (MAGE‐A6) promoted… read more here.
Keywords: lung cancer; non small; small cell; mage ... See more keywords
Expression of the tumor antigens NY-ESO-1, tyrosinase, MAGE-A3, and TPTE in pediatric and adult melanoma: a retrospective case control study
Sign Up to like & getrecommendations! Published in 2024 at "Virchows Archiv"
DOI: 10.1007/s00428-024-03846-0
Abstract: Tumor-associated antigens (TAAs) are potential targets for T cell-based immunotherapy approaches in cutaneous melanoma. BNT111, an investigational lipoplex-formulated mRNA-based therapeutic cancer vaccine encoding melanoma TAAs NY-ESO-1, tyrosinase, MAGE-A3, and TPTE, is undergoing clinical testing in… read more here.
Keywords: tpte; mage; melanoma; tyrosinase mage ... See more keywords
Suppression of MAGE-A10 alters the metastatic phenotype of tongue squamous cell carcinoma cells
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2017.04.009
Abstract: MAGE-A10 is a member of the MAGE protein family (melanoma associated antigen) which is overexpressed in cancer cells. Although MAGE-A10 has been characterized for some time and is generally associated to metastasis its function remains… read more here.
Keywords: cell carcinoma; squamous cell; mage; mage a10 ... See more keywords
Relationship between glucose variability evaluated by continuous glucose monitoring and clinical factors, including glucagon-stimulated insulin secretion in patients with type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2019.107904
Abstract: AIMS To evaluate the clinical factors affecting daily and day-to-day glucose variability by using continuous glucose monitoring. METHODS We performed a cross-sectional analysis of patients with type 2 diabetes mellitus (T2DM) who underwent a glucagon… read more here.
Keywords: mage; clinical factors; variability; glucose variability ... See more keywords
Multi-dynamic modelling reveals strongly time-varying resting fMRI correlations
Sign Up to like & getrecommendations! Published in 2022 at "Medical Image Analysis"
DOI: 10.1016/j.media.2022.102366
Abstract: Highlights • MAGE is multi-dynamic in that it models temporal fluctuations in FC independently from fluctuations in the mean of the activity.• MAGE reveals stronger changes in FC over time than single-dynamic approaches, such as… read more here.
Keywords: time; multi dynamic; time varying; dynamic modelling ... See more keywords
Executive function, repetitive behaviour and restricted interests in neurodevelopmental disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Research in developmental disabilities"
DOI: 10.1016/j.ridd.2021.104166
Abstract: BACKGROUND Individuals with genetic syndromes show unique profiles of repetitive behaviours and restricted interests (RRBs). The executive dysfunction account of RRBs suggests that in autistic (AUT) individuals executive function impairments underpin RRBs, but not communication… read more here.
Keywords: restricted interests; function; aut individuals; function repetitive ... See more keywords
Discovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00185
Abstract: MAGE proteins are cancer testis antigens (CTAs) that are characterized by highly conserved MAGE homology domains (MHDs) and are increasingly being found to play pivotal roles in promoting aggressive cancer types. MAGE-A4, in particular, increases… read more here.
Keywords: mage rad18; potent; mage; discovery structural ... See more keywords
RELATIONSHIP OF SHORT- AND MID-TERM GLUCOSE VARIABILITY WITH BLOOD PRESSURE PROFILE PARAMETERS IN ADOLESCENTS AND YOUNG ADULTS WITH TYPE 1 DIABETES
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0001020760.58195.88
Abstract: Objective: The aim of the study was to investigate the association between blood pressure (BP) profile parameters and short- and mid-term glucose variability (GV) in young individuals with Type 1 Diabetes (T1D). Design and method:… read more here.
Keywords: pressure profile; profile parameters; mage; blood pressure ... See more keywords
Involvement of NY-ESO-1 and MAGE-A4 in the pathogenesis of desmoid tumors
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033908
Abstract: The involvement of New York esophageal squamous cell carcinoma-1 (NY-ESO-1) and melanoma-associated antigen A4 (MAGE-A4) in soft-tissue sarcoma pathogenesis has recently been reported; however, their involvement in desmoid tumors (DTs) remains unknown. This study aimed… read more here.
Keywords: desmoid tumors; positivity; mage; correlation ... See more keywords
Association of homogeneous inflamed gene signature with a better outcome in patients with metastatic melanoma treated with MAGE-A3 immunotherapeutic
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-000384
Abstract: Purpose This study assessed clinical activity, safety and immunogenicity of MAGE-A3 immunotherapeutic in patients with MAGE-A3-positive metastatic melanoma. Patients and methods In this open-label, multicentre, uncontrolled, Phase II study (ClinicalTrials.gov NCT00896480),patients received ≤24 doses of… read more here.
Keywords: mage immunotherapeutic; clinical activity; mage; treatment ... See more keywords