Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2017121275
Abstract: BACKGROUND The slit diaphragm is a specialized adhesion junction between opposing podocytes, establishing the final filtration barrier that prevents passage of proteins from the capillary lumen into the urinary space. Nephrin, the key structural and… read more here.
Keywords: magi1; pbm; slit diaphragm; nephrin pbm ... See more keywords
MAGI1 Inhibits the Proliferation, Migration and Invasion of Glioma Cells
Sign Up to like & getrecommendations! Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s230236
Abstract: Background Membrane-associated guanylate kinase inverted repeat member 1 (MAGI1) acts as a tumor suppressor in a variety of tumors; however, its expression and biological function in glioma are still unknown. Methods MAGI1 expression in glioma… read more here.
Keywords: glioma; migration invasion; proliferation; magi1 ... See more keywords
p90RSK-MAGI1 Module Controls Endothelial Permeability by Post-translational Modifications of MAGI1 and Hippo Pathway
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DOI: 10.3389/fcvm.2020.542485
Abstract: Previously, we reported that post-translational modifications (PTMs) of MAGI1, including S741 phosphorylation and K931 de-SUMOylation, both of which are regulated by p90RSK activation, lead to endothelial cell (EC) activation. However, roles for p90RSK and MAGI1-PTMs… read more here.
Keywords: magi1; p90rsk magi1; post translational; permeability ... See more keywords
MAGI1 inhibits interferon signaling to promote influenza A infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.791143
Abstract: We have shown that membrane-associated guanylate kinase with inverted domain structure-1 (MAGI1), a scaffold protein with six PSD95/DiscLarge/ZO-1 (PDZ) domains, is involved in the regulation of endothelial cell (EC) activation and atherogenesis in mice. In… read more here.
Keywords: magi1; infection; expression; iav infection ... See more keywords