Articles with "magnesiation pyridone" as a keyword



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Directed Zincation or Magnesiation of the 2-Pyridone and 2,7-Naphthyridone Scaffold Using TMP Bases.

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Published in 2017 at "Organic letters"

DOI: 10.1021/acs.orglett.7b02690

Abstract: A regioselective zincation of the 2-pyridone and 2,7-naphthyridone scaffolds has been developed. Zincations of the methoxyethoxymethyl (MEM)-protected compounds using TMP2Zn·2MgCl2·2LiCl (TMP = 2,2,6,6-tetramethylpiperidyl) followed by trapping with electrophiles provided functionalized 2-pyridones and 2,7-naphthyridones. I/Mg exchange… read more here.

Keywords: tmp; pyridone naphthyridone; zincation; magnesiation pyridone ... See more keywords