Articles with "magnesium isoglycyrrhizinate" as a keyword



Magnesium isoglycyrrhizinate blocks fructose‐induced hepatic NF‐&kgr;B/NLRP3 inflammasome activation and lipid metabolism disorder

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Published in 2017 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.05.032

Abstract: &NA; Magnesium isoglycyrrhizinate as a hepatoprotective agent possesses immune modulation and anti‐inflammation, and treats liver diseases. But its effects on immunological‐inflammatory and metabolic profiles for metabolic syndrome with liver injury and underlying potential mechanisms are… read more here.

Keywords: isoglycyrrhizinate; magnesium isoglycyrrhizinate; activation; nlrp3 inflammasome ... See more keywords

Magnesium isoglycyrrhizinate alleviate airway inflammatory responses in ovalbumin-induced mouse model of allergic asthma

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Published in 2022 at "Immunopharmacology and Immunotoxicology"

DOI: 10.1080/08923973.2022.2055567

Abstract: Abstract Objective Asthma is a common chronic airway inflammatory disease, lacking effective therapeutic approaches. Magnesium isoglycyrrhizinate (MgIG) is an anti-inflammatory drug for treating chronic inflammation. However, it is still ambiguous whether MgIG can function in… read more here.

Keywords: allergy induced; airway inflammatory; group; model ... See more keywords

Magnesium isoglycyrrhizinate suppresses bladder cancer progression by modulating the miR-26b/Nox4 axis

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2031677

Abstract: ABSTRACT Magnesium isoglycyrrhizinate (MI), a magnesium salt of 18α-GA stereoisomer, has been reported to exert efficient hepatoprotective activity. However, its effect on bladder cancer remains unclear. The study explored the effects of MI on the… read more here.

Keywords: magnesium isoglycyrrhizinate; mir 26b; bladder cancer; modulating mir ... See more keywords

Magnesium isoglycyrrhizinate shows hepatoprotective effects in a cyclophosphamide-induced model of hepatic injury

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.16629

Abstract: The purpose of the current study was to investigate the effect of Magnesium Isoglycyrrhizinate (GM) on cyclophosphamide (CP)-induced hepatic injury in vivo and in vitro. The results demonstrated that GM exerted a protective effect on… read more here.

Keywords: magnesium isoglycyrrhizinate; hepatic injury; injury; cyclophosphamide induced ... See more keywords

Magnesium Isoglycyrrhizinate Alleviates Arsenic Trioxide-Induced Cardiotoxicity: Contribution of Nrf2 and TLR4/NF-κB Signaling Pathway

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Published in 2021 at "Drug Design, Development and Therapy"

DOI: 10.2147/dddt.s296405

Abstract: Purpose Magnesium isoglycyrrhizinate (MgIG), a single stereoisomer magnesium salt of glycyrrhizic acid, has beneficial effects on the cardiovascular system through anti-inflammatory, anti-oxidation, and anti-apoptotic actions. However, MgIG has not been shown to provide protection against… read more here.

Keywords: arsenic trioxide; induced cardiotoxicity; magnesium isoglycyrrhizinate; cardiotoxicity ... See more keywords