Magnolol prevented brain injury through the modulation of Nrf2-dependent oxidative stress and apoptosis in PLP-induced mouse model of multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2022 at "Naunyn-Schmiedeberg's archives of pharmacology"
DOI: 10.1007/s00210-022-02230-6
Abstract: Multiple sclerosis (MS) is an immune-mediated chronic inflammatory demyelinating disease of the central nervous system (CNS). The aim of the current study was to investigate the effects of magnolol in an experimental autoimmune encephalomyelitis (EAE)… read more here.
Keywords: magnolol; multiple sclerosis; brain; oxidative stress ... See more keywords
P32 The effects of Magnolia poasana extracts on vascular function and platelet aggregation – A comparison with magnolol
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2017.06.033
Abstract: Magnolol is a biologically active compound isolated from Magnolia officinalis, which has been used as a traditional medicine for the treatment of stroke and myocardial infarction, and exerts vasodilator and anti-platelet activity [1] . We… read more here.
Keywords: medicine; effects magnolia; p32 effects; magnolol ... See more keywords
Magnolol abrogates chronic mild stress‐induced depressive‐like behaviors by inhibiting neuroinflammation and oxidative stress in the prefrontal cortex of mice
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.03.031
Abstract: ABSTRACT Magnolol, the main constituent of Magnolia officinalis, has been shown to produce antidepressant‐like effect in rodents. Growing evidence shows that neuroinflammation, oxidative stress and neuroendocrine contribute to the pathogenesis of major depression. Here, the… read more here.
Keywords: neuroinflammation oxidative; magnolol; depressive like; stress ... See more keywords
Magnolol prevents ossified tendinopathy by inhibiting PGE2‐induced osteogenic differentiation of TDSCs
Sign Up to like & getrecommendations! Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2019.02.010
Abstract: Abstract Magnolol is a compound that is extracted from magnolia, is used in Chinese medicine and is a type of lignan. Magnolol has various anti‐inflammation, anti‐proliferation and pro‐autophagy effects. Ossified tendinopathy affects many athletes and… read more here.
Keywords: magnolol; pge2 induced; osteogenic differentiation; ossified tendinopathy ... See more keywords
In-vitro and in-vivo anti-allergic effects of magnolol on allergic rhinitis via inhibition of ORAI1 and ANO1 channels.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2022.115061
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Flos Magnoliae (the dried flower buds of Magnolia biondii Pamp, FM) is a known herbal traditional medicine used for the symptomatic relief of nasal congestion and rhinorrhea caused by rhinitis and sinusitis. Magnolol,… read more here.
Keywords: magnolol; allergic rhinitis; orai1 ano1; anti allergic ... See more keywords
Magnolol protects Saccharomyces cerevisiae antioxidant-deficient mutants from oxidative stress and extends yeast chronological life span.
Sign Up to like & getrecommendations! Published in 2019 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fnz065
Abstract: We investigated the protective effect of a natural polyphenol, magnolol, on Saccharomyces cerevisiae cells under oxidative stress, and during aging. Our results showed the sensitivity of S. cerevisiae antioxidant gene deficient mutants (sod1∆, sod2∆, cta1∆,… read more here.
Keywords: saccharomyces cerevisiae; deficient mutants; magnolol; stress ... See more keywords
Magnolol reduces myocardial injury induced by renal ischemia and reperfusion
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000727
Abstract: Background: Magnolol is a component of the bark of Magnolia officinalis, which is a traditional herbal remedy used in China. In this study, we investigated whether magnolol can reduce myocardial injury induced by renal ischemia… read more here.
Keywords: magnolol; myocardial injury; induced renal; reperfusion ... See more keywords
Magnolol-mediated regulation of plasma triglyceride through affecting lipoprotein lipase activity in apolipoprotein A5 knock-in mice
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0192740
Abstract: Hyperlipidemia is a risk factor of arteriosclerosis, stroke, and other coronary heart disease, which has been shown to correlate with single nucleotide polymorphisms of genes essential for lipid metabolism, such as lipoprotein lipase (LPL) and… read more here.
Keywords: knock mice; magnolol; mice; plasma triglyceride ... See more keywords
Characterization of Alternaria porri causing onion purple blotch and its antifungal compound magnolol identified from Caryodaphnopsis baviensis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0262836
Abstract: Alternaria porri (Ellis) Clf. causes purple blotch disease on Allium plants which results in the reduction of crop yields and quality. In this study, to efficiently find natural antifungal compounds against A. porri, we optimized… read more here.
Keywords: magnolol; baviensis; purple blotch; compound ... See more keywords
Magnolol inhibits growth and induces apoptosis in esophagus cancer KYSE-150 cell lines via the MAP kinase pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2019.07.46
Abstract: Background Magnolol has shown anti-cancer activity against a variety of cancers, such as liver, breast, lung and colon cancer. However, the role of magnolol in esophagus cancer cells is unknown. Methods In this study, esophagus… read more here.
Keywords: cancer; cell; esophagus cancer; magnolol ... See more keywords
Accessing Apoptosis Induction and Metastasis Inhibition Effect of Magnolol on Triple Negative Breast Cancer In Vitro
Sign Up to like & getrecommendations! Published in 2023 at "In Vivo"
DOI: 10.21873/invivo.13177
Abstract: Background/Aim: Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer that still requires improvement in treatment. Magnolol extract, derived from the bark of Magnolia officinalis, has traditionally been used in Asia to treat… read more here.
Keywords: magnolol; breast cancer; apoptosis; tnbc ... See more keywords