Novel cinnamic acid magnolol derivatives as potent α-glucosidase and α-amylase inhibitors: Synthesis, in vitro and in silico studies.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105291
Abstract: In this study, twenty novel cinnamic acid magnolol derivatives were synthesized, and screened for their anti-hyperglycemic potential. All synthesized compounds exhibited good to moderate α-glucosidase and α-amylase inhibitory activities with IC50 values: 5.11 ± 1.46-90.26 ± 1.85 µM and 4.27 ± 1.51-49.28 ± 2.54 µM… read more here.
Keywords: novel cinnamic; cinnamic acid; magnolol derivatives; glucosidase amylase ... See more keywords
Natural magnolol derivatives as platform chemicals for bio-based phthalonitrile thermoset: Achieving high performances without an external curing agent
Sign Up to like & getrecommendations! Published in 2021 at "Polymer"
DOI: 10.1016/j.polymer.2021.123814
Abstract: Abstract Bio-based polymers with better comprehensive properties, showing more competitiveness than their petroleum-based counterparts in high-tech fields is an increasingly trend but also a formidable challenge. In the study, bio-based phthalonitrile precursors were synthesized from… read more here.
Keywords: platform chemicals; natural magnolol; based phthalonitrile; bio based ... See more keywords
Design, Synthesis, and Structure-Activity Relationship Studies of Magnolol Derivatives as Antifungal Agents.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c01838
Abstract: Plant pathogenic fungi seriously affect agricultural production and are difficult to control. The discovery of new leads based on natural products is an important way to innovate fungicides. In this study, 30 natural-product-based magnolol derivatives… read more here.
Keywords: antifungal agents; magnolol derivatives; activity relationship; structure activity ... See more keywords