Bis(trifluoromethylsulfonyl)imide-based frozen ionic liquid for the hollow-fiber solid-phase microextraction of dichlorodiphenyltrichloroethane and its main metabolites.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700429
Abstract: 1-Hexadecyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide is a solid-phase ionic organic material under ambient temperature and is considered as a kind of "frozen" ionic liquid. Because of their solid-state and ultra-hydrophobicity, "frozen" ionic liquids are able to be confined… read more here.
Keywords: frozen ionic; main metabolites; dichlorodiphenyltrichloroethane main; solid phase ... See more keywords
Analysis of tamoxifen and its main metabolites in plasma samples of breast cancer survivor female athletes: Multivariate and chemometric optimization.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202100899
Abstract: A sensitive method based on liquid chromatography combined with a diode array detector was developed and validated to simultaneously determine tamoxifen, and its active metabolites N-desmethyltamoxifen, 4-hydroxytamoxifen, and endoxifen in human plasma samples. The green… read more here.
Keywords: analysis tamoxifen; tamoxifen main; main metabolites; tamoxifen ... See more keywords
Fate of priority pharmaceuticals and their main metabolites and transformation products in microalgae-based wastewater treatment systems.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2019.121771
Abstract: The present study evaluates the removal capacity of two high rate algae ponds (HRAPs) to eliminate 12 pharmaceuticals (PhACs) and 26 of their corresponding main metabolites and transformation products. The efficiency of these ponds, operating… read more here.
Keywords: metabolites transformation; treatment; main metabolites; wastewater treatment ... See more keywords
Pharmacokinetics, excretion of 8‐cetylberberine and its main metabolites in rat urine
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2016.09.022
Abstract: Graphical abstract Figure. No Caption available. HighlightsThe pharmacokinetics of BBR and its derivatives including 8‐cetylberberine (8‐BBR‐C16) in rat plasma was studied by high performance liquid chromatography (HPLC).The excretion of 8‐BBR‐C16 in rat urine and feces… read more here.
Keywords: bbr; bbr c16; rat urine; main metabolites ... See more keywords
Development and validation of a quantitative assay for the determination of cinacalcet and its main metabolites in human plasma using RP-HPLC method
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DOI: 10.1016/j.microc.2016.10.017
Abstract: A novel and sensitive methodology for the quantitative determination of cinacalcet (CIN), and its main metabolites (M2a-Glu, M2b-Glu, M5, and M6) in plasma sample is suggested. The analytical assay is based on reversed-phase high-performance liquid… read more here.
Keywords: determination; human plasma; main metabolites; method ... See more keywords
ABCG2 transporter plays a key role in the biodistribution of melatonin and its main metabolites
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pineal Research"
DOI: 10.1111/jpi.12849
Abstract: The ATP‐binding cassette G2 (ABCG2) is an efflux transporter expressed in the apical membrane of cells from a large number of tissues, directly affecting bioavailability, tissue accumulation, and secretion into milk of both xenobiotics and… read more here.
Keywords: melatonin main; transporter; main metabolites; milk ... See more keywords
Selective inhibition of cyclooxygenase‐2 by enflicoxib, its enantiomers and its main metabolites in vitro in canine blood
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Veterinary Pharmacology and Therapeutics"
DOI: 10.1111/jvp.13042
Abstract: Abstract Enflicoxib is approved for the treatment of pain and inflammation in canine osteoarthritis. The objective of this work was to assess the mechanistic basis of enflicoxib therapy investigating the COX inhibitory activity of enflicoxib… read more here.
Keywords: enantiomers main; inhibition; cox; main metabolites ... See more keywords
The interplay between pharmacogenetics, concomitant drugs and blood levels of amitriptyline and its main metabolites.
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DOI: 10.2217/pme-2021-0022
Abstract: Background: The research considers the impact of genotype-inferred variability on blood levels of amitriptyline and its main metabolites, as may be moderated by phenocopying. Patients & methods: CYP2D6 and CYP2C19 genotypes, and serum concentrations of… read more here.
Keywords: levels amitriptyline; amitriptyline main; blood levels; inhibition risk ... See more keywords
Three main metabolites from Wolfiporia cocos (F. A. Wolf) Ryvarden & Gilb regulate the gut microbiota in mice: A comparative study using microbiome-metabolomics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.911140
Abstract: Wolfiporia cocos (F. A. Wolf) Ryvarden & Gilb, also known as Poria cocos is an ancient edible and medicinal mushroom that has been valued for thousands of years for its tranquilizing, diuretic, and spleen-enhancing properties.… read more here.
Keywords: wolfiporia cocos; gut microbiota; main metabolites; wolf ryvarden ... See more keywords