A pair of transporters controls mitochondrial Zn2+ levels to maintain mitochondrial homeostasis.
Sign Up to like & getrecommendations! Published in 2021 at "Protein & cell"
DOI: 10.1007/s13238-021-00881-4
Abstract: Zn2+ is required for the activity of many mitochondrial proteins, which regulate mitochondrial dynamics, apoptosis and mitophagy. However, it is not understood how the proper mitochondrial Zn2+ level is achieved to maintain mitochondrial homeostasis. Using… read more here.
Keywords: transporters controls; mitochondrial homeostasis; maintain mitochondrial; mitochondrial zn2 ... See more keywords
Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy.
Sign Up to like & getrecommendations! Published in 2023 at "Brain pathology"
DOI: 10.1111/bpa.13157
Abstract: Mitochondrial encephalomyopathies (ME) are frequently associated with mutations of mitochondrial DNA, but the pathogenesis of a subset of ME (sME) remains elusive. Here we report that haploinsufficiency of a mitochondrial inner membrane protein, Mic60, causes… read more here.
Keywords: mic60; essential maintain; mic60 essential; maintain mitochondrial ... See more keywords