Cost-effectiveness of Maintenance Therapy Based on Molecular Classification Following Treatment of Primary Epithelial Ovarian Cancer in the United States
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.28620
Abstract: Key Points Question Is maintenance therapy after first-line treatment of ovarian cancer cost-effective in the United States? Findings In this economic evaluation of maintenance strategies after first-line ovarian cancer therapy, no maintenance regimen—including olaparib, olaparib-bevacizumab,… read more here.
Keywords: maintenance; cost; ovarian cancer; maintenance therapy ... See more keywords
Evaluation of Budesonide-Formoterol for Maintenance and Reliever Therapy Among Patients With Poorly Controlled Asthma
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.0615
Abstract: This systematic review and meta-analysis evaluates whether, for patients with poorly controlled asthma, switching to single inhaler combination budesonide-formoterol maintenance and reliever therapy is associated with longer time to first severe asthma exacerbation compared with… read more here.
Keywords: poorly controlled; maintenance; patients poorly; controlled asthma ... See more keywords
Association of Maintenance Intravenous Immunoglobulin With Prevention of Relapse in Adult Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.0489
Abstract: Importance Recent studies suggest that maintenance intravenous immunoglobulin (IVIG) may be an effective treatment to prevent relapses in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD); however, most of these studies had pediatric cohorts, and few studies… read more here.
Keywords: maintenance ivig; adult; maintenance; disease ... See more keywords
Maintenance Therapy With Panitumumab Alone vs Panitumumab Plus Fluorouracil-Leucovorin in Patients With RAS Wild-Type Metastatic Colorectal Cancer: A Phase 2 Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2019.1467
Abstract: Importance Few studies are available on the role of maintenance strategies after induction treatment regimens based on anti-epidermal growth factor receptors, and the optimal regimen for an anti-epidermal growth factor receptors-based maintenance treatment in patients… read more here.
Keywords: arm; panitumumab plus; maintenance; treatment ... See more keywords
One‐year weight loss maintenance outcomes following a worksite‐based weight reduction program among Japanese men with cardiovascular risk factors
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Occupational Health"
DOI: 10.1002/1348-9585.12039
Abstract: Worksite‐based programs present a simple and effective approach to facilitate weight reduction in employees. Despite the importance of 1‐year weight loss maintenance, studies have generally focused on the short‐term effects of weight reduction programs. In… read more here.
Keywords: reduction; weight reduction; maintenance; weight loss ... See more keywords
Unique effects of The transporters animated series and of parental support on emotion recognition skills of children with ASD: Results of a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2017 at "Autism Research"
DOI: 10.1002/aur.1717
Abstract: Emotion recognition (ER) and understanding deficits are characteristic of autism spectrum disorder (ASD). The Transporters (TT) animated series has shown promising results in teaching children with ASD to recognize emotions, with mixed findings about generalization… read more here.
Keywords: generalization; maintenance; series; parental support ... See more keywords
Positive allometry of sexually selected traits: Do metabolic maintenance costs play an important role?
Sign Up to like & getrecommendations! Published in 2021 at "BioEssays"
DOI: 10.1002/bies.202000183
Abstract: Sexual selection drives the evolution of some of the most exaggerated traits in nature. Studies on sexual selection often focus on the size of these traits relative to body size, but few focus on energetic… read more here.
Keywords: selected traits; maintenance; size; maintenance costs ... See more keywords
Real‐world data for lenalidomide maintenance in responding patients of diffuse large B‐cell lymphoma
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DOI: 10.1002/cam4.5790
Abstract: Approximately 40% patients of diffuse large B‐cell lymphoma (DLBCL) would develop disease recurrence/progression after first‐line R‐CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) induction therapy, with highly poor prognosis. An effective strategy to prolong the survival… read more here.
Keywords: maintenance; cell lymphoma; lenalidomide maintenance; large cell ... See more keywords
Exposure‐Response Characterization of Tofacitinib Efficacy in Moderate to Severe Ulcerative Colitis: Results From Phase II and Phase III Induction and Maintenance Studies
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2601
Abstract: Tofacitinib is an oral small molecule JAK inhibitor for the treatment of ulcerative colitis. Relationships between plasma tofacitinib concentration and efficacy were characterized using exposure‐response (E‐R) models, with demographic and disease covariates evaluated as potential… read more here.
Keywords: maintenance; tofacitinib; efficacy; phase iii ... See more keywords
Canonical and non‐canonical functions of STAT in germline stem cell maintenance
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DOI: 10.1002/dvdy.576
Abstract: Maintenance of the Drosophila male germline stem cells (GSCs) requires activation of the Janus kinase/signal transducer and activators of transcription (JAK/STAT) pathway by niche signals. The precise role of JAK/STAT signaling in GSC maintenance, however,… read more here.
Keywords: canonical functions; canonical non; maintenance; non canonical ... See more keywords
Joint effects of female preference intensity and frequency‐dependent predation on the polymorphism maintenance in aposematic sexual traits
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.9356
Abstract: Abstract Maintenance of variation in aposematic traits within and among populations is paradoxical because aposematic species are normally under positive frequency‐dependent predation (PFD), which is expected to erode variation. Aposematic traits can evolve in an… read more here.
Keywords: dependent predation; aposematic traits; polymorphism; frequency dependent ... See more keywords