The structural maintenance of chromosomes 5 is a possible biomarker for individualized treatment of colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5074
Abstract: Although the understanding of resistance to oxaliplatin (OXA) chemotherapy in colorectal cancer (CRC) has been sought for many years, drug tolerance remains a major challenge for cancer therapy. Revealing the molecular mechanism of OXA resistance… read more here.
Keywords: cancer; structural maintenance; possible biomarker; colorectal cancer ... See more keywords
The Role of Structural Maintenance of Chromosomes Complexes in Meiosis and Genome Maintenance: Translating Biomedical and Model Plant Research Into Crop Breeding Opportunities
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DOI: 10.3389/fpls.2021.659558
Abstract: Cohesin is a multi-unit protein complex from the structural maintenance of chromosomes (SMC) family, required for holding sister chromatids together during mitosis and meiosis. In yeast, the cohesin complex entraps sister DNAs within tripartite rings… read more here.
Keywords: plant; meiosis; maintenance; structural maintenance ... See more keywords
Prognostic Relevance of Structural Maintenance of Chromosomes 4 Overexpression in Pediatric Acute Lymphoblastic Leukemia.
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DOI: 10.7754/clin.lab.2021.210852
Abstract: BACKGROUND Acute lymphoblastic leukemia (ALL) is the most common cancer in children. Abnormal expression of structural maintenance of chromosomes (SMC) 4 has been observed in multiple tumors and plays a vital role in cancer development.… read more here.
Keywords: structural maintenance; smc4 expression; expression; lymphoblastic leukemia ... See more keywords