A Germline‐Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells
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DOI: 10.1002/advs.202203631
Abstract: Maintenance and differentiation of germline stem and progenitor cells (GSPCs) is important for sexual reproduction. Here, the authors identify zebrafish pld6 as a novel germline‐specific gene by cross‐analyzing different RNA sequencing results, and find that… read more here.
Keywords: maintenance differentiation; germline specific; mitochondrial fusion; germline ... See more keywords
The transcriptional regulator Zfat is essential for maintenance and differentiation of the adipocytes
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DOI: 10.1002/jcb.29890
Abstract: Adipocytes play crucial roles in the control of whole‐body energy homeostasis. Differentiation and functions of the adipocytes are regulated by various transcription factors. Zfat (zinc‐finger protein with AT‐hook) is a transcriptional regulator that controls messenger… read more here.
Keywords: transcriptional regulator; maintenance differentiation; differentiation; zfat ... See more keywords
R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors
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DOI: 10.7554/elife.53895
Abstract: During kidney development, WNT/β-catenin signalling has to be tightly controlled to ensure proliferation and differentiation of nephron progenitor cells. Here, we show in mice that the signalling molecules RSPO1 and RSPO3 act in a functionally… read more here.
Keywords: differentiation; nephron progenitors; nephron; spondin signalling ... See more keywords